New MRI method could spare thousands from unnecessary kidney surgery

NCT ID NCT03470285

Completed Diagnosis Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This completed study tested whether a special type of MRI (multiparametric MRI) can accurately tell the difference between benign and malignant small kidney tumors. About 387 adults with small solid kidney masses (1.5-4 cm) were scanned before surgery or biopsy. The goal was to see if the MRI could reliably identify benign tumors, potentially allowing some patients to avoid unnecessary surgery. The study involved 18 centers and multiple radiologists to check consistency.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Multiparametric MR imaging (mpMRI)
What this could lead to: If successful, mpMRI could help doctors decide which small kidney tumors need surgery and which can be safely monitored, reducing unnecessary operations.
What could go wrong: This is a completed diagnostic accuracy study, not a treatment trial. The MRI technique may not be accurate enough in all cases, and results depend on radiologist interpretation.

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Conditions

The condition(s) this trial relates to.

kidney cancer renal carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RENAL CANCER

Contacts and locations

Locations

APHM - Hôpital de la Conception

Marseille, 13385, France
APHP - Henri Mondor

Créteil, 94010, France
APHP - Hôpital Bichat

Paris, France
APHP - Hôpital Bicêtre

Le Kremlin-Bicêtre, 94275, France
APHP - Hôpital Necker

Paris, 75743, France
APHP - Hôpital Tenon

Paris, 75020, France
CHRU Lille

Lille, 59000, France
CHU Angers

Angers, 49933, France
CHU Bordeaux

Bordeaux, 33076, France
CHU Lyon

Lyon, 69444, France
CHU Nancy

Nancy, 54511, France
CHU Nice

Nice, 06001, France
CHU Rennes

Rennes, 35033, France
CHU Rouen

Rouen, 76031, France
CHU Strasbourg

Strasbourg, 67091, France
CHU Toulouse

Toulouse, 31062, France
CHU Tours

Tours, 37044, France
CHU de Grenoble

Grenoble, France

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