New MRI method could spare thousands from unnecessary kidney surgery

NCT ID NCT03470285

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested whether a special type of MRI (multiparametric MRI) can accurately tell the difference between benign and malignant small kidney tumors. About 387 adults with small solid kidney masses (1.5-4 cm) were scanned before surgery or biopsy. The goal was to see if the MRI could reliably identify benign tumors, potentially allowing some patients to avoid unnecessary surgery. The study involved 18 centers and multiple radiologists to check consistency.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Multiparametric MR imaging (mpMRI)

What this could lead to

If successful, mpMRI could help doctors decide which small kidney tumors need surgery and which can be safely monitored, reducing unnecessary operations.

What could go wrong

This is a completed diagnostic accuracy study, not a treatment trial. The MRI technique may not be accurate enough in all cases, and results depend on radiologist interpretation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

kidney cancer renal carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHM - Hôpital de la Conception

    Marseille, 13385, France

  • APHP - Henri Mondor

    Créteil, 94010, France

  • APHP - Hôpital Bichat

    Paris, France

  • APHP - Hôpital Bicêtre

    Le Kremlin-Bicêtre, 94275, France

  • APHP - Hôpital Necker

    Paris, 75743, France

  • APHP - Hôpital Tenon

    Paris, 75020, France

  • CHRU Lille

    Lille, 59000, France

  • CHU Angers

    Angers, 49933, France

  • CHU Bordeaux

    Bordeaux, 33076, France

  • CHU Lyon

    Lyon, 69444, France

  • CHU Nancy

    Nancy, 54511, France

  • CHU Nice

    Nice, 06001, France

  • CHU Rennes

    Rennes, 35033, France

  • CHU Rouen

    Rouen, 76031, France

  • CHU Strasbourg

    Strasbourg, 67091, France

  • CHU Toulouse

    Toulouse, 31062, France

  • CHU Tours

    Tours, 37044, France

  • CHU de Grenoble

    Grenoble, France