PULMONARY EMBOLISM

This study tested whether taking a low dose of the blood thinner apixaban for a longer time could prevent blood clots from returning in people who already had a clot caused by a temporary risk factor (like surgery or immobility). 600 adults at high risk for another clot were rand…

This study tested a device called the Vertex Pulmonary Embolectomy System in 123 people with a sudden, severe blood clot in the lungs (pulmonary embolism). The goal was to see if removing the clot could reduce strain on the right side of the heart and keep patients safe. The main…

This study tested a special filter placed in a large vein to catch blood clots before they reach the lungs. It included 50 people who could not take blood-thinning medicine. Researchers measured how often the filter was successfully placed and removed, and tracked any problems.

This study tested a device called FlowTriever that removes blood clots from the lungs, comparing it to standard clot-busting drugs. About 692 adults with acute pulmonary embolism (a serious lung clot) took part. The goal was to see if the device could lower the chance of death, b…

This study tested a device called FlowTriever2 to remove blood clots from the lungs of 50 people with a serious condition called pulmonary embolism. The goal was to see if the device is safe and can quickly lower blood pressure in the lungs. Participants had symptoms for up to tw…

This study tested a new device called the Hēlo PE Thrombectomy System to remove blood clots from the lungs in people with acute submassive pulmonary embolism. The goal was to see if the device is safe and can quickly improve heart function. 177 participants were enrolled, and the…

This study tested a new scoring system (4PEPS) to help emergency doctors decide if a patient with symptoms like chest pain or shortness of breath really needs a lung scan for a pulmonary embolism (a blood clot in the lungs). Over 3,000 patients from 20 hospitals took part. Half t…

This study looked at whether a leg vein ultrasound could improve how doctors diagnose a repeat pulmonary embolism (a blood clot in the lung). Researchers studied 115 adults hospitalized with symptoms like sudden shortness of breath or chest pain. They compared the ultrasound resu…

This study looked at whether a simple checklist called the YEARS algorithm can safely rule out dangerous blood clots in the lungs (pulmonary embolism) in people with active cancer, without needing a CT scan. About 700 participants were randomly assigned to either the YEARS approa…

This study tested a new CT scan method that creates a map of blood flow in the lungs to diagnose pulmonary embolism (blood clots). Researchers compared this new technique to the standard scan in 30 patients. The goal was to see if the new method is accurate and could provide both…

This study tested whether a special PET/CT scan (V/Q PET/CT) can accurately diagnose pulmonary embolism (a blood clot in the lungs) compared to the standard CT scan. About 100 adults with suspected first-time clots took part. The goal was to see if the new scan is as good or bett…

This study looked at nearly 19,000 people having hip or knee replacement surgery to find out which blood thinner works best to prevent dangerous blood clots. The three medicines compared were aspirin, low-dose warfarin, and rivaroxaban. Researchers tracked deaths, clots, and blee…

This study tested whether a home rehabilitation program with daily physical activity tasks and heart rate monitoring could improve recovery in people who had a pulmonary embolism (a blood clot in the lungs). 32 adults who had a moderate to severe clot participated. The program wa…

This study followed 88 adults diagnosed with pulmonary embolism (blood clots in the lungs) during April 2020, the peak of the COVID-19 pandemic in France. Researchers compared complications like chronic lung disease, repeat clots, high blood pressure in the lungs, and death over …

This study tested whether a 3D CT scan technique could measure changes in lung blood vessels after standard blood thinner treatment for pulmonary embolism (blood clots in the lungs). Ten adults with acute clots had a CT scan before and 48 hours after starting blood thinners. The …

This study tested a new step-by-step method called SEARCH to better classify what happens to people after a pulmonary embolism (a blood clot in the lungs). Researchers looked at 150 adults to see if different doctors using the same method would agree on the diagnosis and if the d…

This study tracked 11,000 COVID-19 patients to see how often they developed dangerous blood clots in arteries or veins. Researchers looked at risk factors, treatments, and outcomes over 30 and 90 days. The goal was to better understand and prevent these complications.

This study tested whether sending safety alerts to pharmacists instead of doctors leads to faster changes in blood thinner prescriptions. Researchers enrolled 306 healthcare providers and compared how quickly each group responded to alerts. The goal was to find the best way for d…

This study looked at whether semaglutide, a GLP-1 agonist used for diabetes, can reduce inflammation in people with acute pulmonary embolism (a blood clot in the lung). 18 participants took the drug for 4 weeks, and researchers measured changes in blood markers of inflammation. T…

This study looked at 744 people who had a blood clot before to see if doctors can better predict when a new clot will happen. Researchers tested three different checklists (called clinical decision rules) to see how well they work. The goal is to help doctors correctly diagnose n…

This study looked at 40 adults who had a pulmonary embolism (a blood clot in the lungs) to see if those with sleep-disordered breathing had worse short-term outcomes or a higher chance of the clot coming back within a year. Participants were monitored for one year, and recurrence…

This study measured levels of free DNA and nucleosomes in the blood of 137 women to see if these markers differ between those with pregnancy complications (like preeclampsia or blood clots) and healthy women (pregnant or not). The goal was to understand if these markers could hel…