Which blood thinner is safer? Head-to-Head trial pits rivaroxaban against apixaban
NCT ID NCT03266783
First seen Nov 17, 2025 · Last updated May 23, 2026 · Updated 20 times
Summary
This study compared two blood thinners, rivaroxaban and apixaban, to see which causes fewer bleeding problems in people with blood clots in the legs or lungs. About 2,760 adults took part, and researchers tracked serious and minor bleeding events. The goal was to help doctors choose the safer option for treating venous thromboembolism.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alberta Health Sciences
Edmonton, Alberta, Canada
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CHU de Québec-Université Laval
Québec, Quebec, Canada
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Hamilton General Hospital
Hamilton, Ontario, Canada
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Hôpital Sacré-Coeur de Montréal
Montreal, Quebec, Canada
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Jewish General Hospital
Montreal, Quebec, H3T 1E2, Canada
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Juravinski Hospital
Hamilton, Ontario, Canada
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Kingston General Hospital
Kingston, Ontario, Canada
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London Health Sciences Center
London, Ontario, N6A 5W9, Canada
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McGill University Health Center
Montreal, Quebec, H4A 3J1, Canada
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QEII Health Science Centre
Halifax, Nova Scotia, B3H 2Y9, Canada
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St. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada
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St. Mary's Hospital
Montreal, Quebec, Canada
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St. Paul's Hospital
Vancouver, British Columbia, Canada
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The Ottawa Hospital - General Campus
Ottawa, Ontario, K1H 8L6, Canada
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The Royal College of Surgeons in Ireland/Mater Misericordiae University Hospital
Dublin, Ireland
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The University of Sydney
Darlington, New South Wales, 200606, Australia
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UHN - Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
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University of Calgary
Calgary, Alberta, Canada
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University of Sherbrooke
Sherbrooke, Quebec, Canada
Conditions
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