New device clears lung clots, eases heart strain in emergency study

NCT ID NCT06576427

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study tested a device called the Vertex Pulmonary Embolectomy System in 123 people with a sudden, severe blood clot in the lungs (pulmonary embolism). The goal was to see if removing the clot could reduce strain on the right side of the heart and keep patients safe. The main measures were changes in heart chamber size on CT scans and any major complications like bleeding or device-related injuries within 48 hours.

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Contacts and locations

Locations

  • Ascension Sacred Heart

    Pensacola, Florida, 32504, United States

  • Baylor Scott & White

    Plano, Texas, 75024, United States

  • Carilion

    Roanoke, Virginia, 24014, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • European Health Center Otwock

    Otwock, 05-400, Poland

  • Hartford Hospital

    Hartford, Connecticut, 06102, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Henry Ford St John

    Detroit, Michigan, 48236, United States

  • MUSC

    Charleston, South Carolina, 29425, United States

  • Medical University of Vienna

    Vienna, Austria

  • Medical University of Warsaw

    Warsaw, Poland

  • NYU Langone Health

    New York, New York, 10016, United States

  • Northwell Health

    Staten Island, New York, 10305, United States

  • Penn Presbyterian

    Philadelphia, Pennsylvania, 19104, United States

  • St Clair Health

    Pittsburgh, Pennsylvania, 15243, United States

  • St. John Paul II Hospital

    Krakow, Poland

  • Turkey Creek Medical Center

    Knoxville, Tennessee, 37934, United States

  • UPMC Presbyterian

    Pittsburgh, Pennsylvania, 15213, United States

  • University Hospital Basel

    Basel, 4031, Switzerland

  • University of North Carolina

    Chapel Hill, North Carolina, 27517, United States

  • Wake Forest Medical Center

    Winston-Salem, North Carolina, 27157, United States

  • Westchester Medical Center

    Valhalla, New York, 10595, United States

Conditions

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