Could a simple score cut down on unnecessary lung scans?

NCT ID NCT06015529

Completed Diagnosis Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tested a new way to decide if someone with a suspected blood clot in the lung needs a scan. The 4PEPS score uses 12 simple factors and a blood test to classify risk into four levels. Over 3,000 patients in 20 emergency departments took part. The goal was to see if using this score could safely reduce the number of CT scans and other imaging tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 4PEPS diagnostic strategy (a clinical scoring system using 12 variables and D-dimer levels)
What this could lead to: If successful, this strategy could reduce unnecessary chest scans and radiation exposure for patients with suspected pulmonary embolism, while maintaining safety.
What could go wrong: The trial is completed but results are not yet published. The strategy may not reduce imaging as hoped, or could miss some cases of pulmonary embolism.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY EMBOLISM

Contacts and locations

Locations

AP HP Clamart

Clamart, France
CH Agen

Agen, France
CH Argenteuil

Argenteuil, France
CH Arpajon

Arpajon, France
CH La Rochelle

La Rochelle, France
CH Rochefort

Rochefort, France
CH Troyes

Troyes, France
CH Versailles

Le Chesnay, France
CHR Metz Thionville

Metz, France
CHU Angers

Angers, 49000, France
CHU Clermont Ferrand

Clermont-Ferrand, France
CHU Grenoble

Grenoble, France
CHU Limoges

Limoges, France
CHU Liège

Liège, Belgium
CHU Lyon

Lyon, France
CHU Nantes

Nantes, France
CHU Nice

Nice, France
CHU Poitiers

Poitiers, France
CHU Rouen

Rouen, France
CHU Toulouse

Toulouse, France
CHU Tours

Tours, France
Cliniques Bruxelles

Brussels, Belgium
GH Paris

Paris, France

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