University Hospital, Angers

This study is testing whether starting personalized nutrition support within two days of a severe stroke can help reduce deaths in the first month. In the test group, a dietitian will assess each patient and create a feeding plan, which may include special foods or tube feeding i…

This study is testing a treatment called extracorporeal phototherapy (ECP) for people with chronic kidney transplant rejection. ECP involves taking a patient's blood cells, treating them with ultraviolet light, and returning them to the body to calm the immune system. Researchers…

This study is testing whether patients with primary liver cancer can safely receive their artery-based treatments and recover at home instead of staying in the hospital. It will compare patient satisfaction, safety, and costs between the two care approaches over seven months. The…

This study is testing whether using a simple early warning system can help patients with serious blood cancers like leukemia and lymphoma. The system uses regular checks of vital signs (like heart rate and breathing) to identify patients at high risk of dangerous complications. I…

This study is testing if a more coordinated care plan helps people with persistent or recurring low back pain. It involves 500 working adults in France. The goal is to see if better teamwork between a person's doctor, physical therapist, and workplace health service improves reco…

This study aims to find the best timing for putting critically ill patients with severe breathing failure on a ventilator. It will compare a 'liberal' strategy (using the ventilator earlier) with a 'restrictive' strategy (trying to avoid it longer) in 200 adult patients. The goal…

This study aims to see if regularly checking pembrolizumab drug levels in the blood helps doctors use this lung cancer treatment more effectively. Researchers will follow 75 adults with non-small cell lung cancer who are already receiving pembrolizumab treatment. They'll monitor …

This study is checking if a new automated system for calculating a simple blood test score (FIB4) is a good way to find people with advanced liver scarring in the general population. It will enroll about 500 adults whose blood tests show a high FIB4 score. The goal is to see if t…

This study is testing a detailed brain mapping technique to better predict which children with severe, medication-resistant epilepsy will become seizure-free after surgery. It will involve 120 children who are already being considered for surgery. The goal is to use this new scan…

This study is testing whether special MRI scans can accurately diagnose an aggressive form of fatty liver disease called NASH. Currently, doctors must perform a painful liver biopsy to confirm NASH. Researchers will compare MRI results from 60 adults with biopsy results to see if…

This study aims to find the best non-invasive testing strategy to diagnose advanced liver scarring (fibrosis) in people with fatty liver disease (NAFLD). Researchers will compare two different step-by-step approaches that combine simple blood tests with specialized scans to accur…

This study is testing a new care pathway for people with knee sprains. It compares using a quick, automated knee stability test (ADL) right after an emergency room visit to the standard approach of waiting for an MRI scan. The goal is to see if this faster diagnosis method leads …

This study is testing if a daily pill (rivaroxaban) works as well as or better than daily injections (LMWH) at preventing dangerous blood clots in people with serious leg injuries who need a cast or brace. It focuses on patients identified as high-risk for clots. Researchers will…

This study is testing whether regular karate practice can improve the mental health and quality of life of medical students, who often experience high stress and anxiety. Researchers will enroll 90 students from the University of Angers to see if karate helps with self-esteem, sl…

This study is testing whether specially designed video games that combine physical movement with mental challenges can help people with Huntington's disease. Researchers will compare two different exercise programs in 40 participants to see if they improve balance, walking, memor…

This study is testing a new home-based walking program that uses a special treadmill and virtual reality games. It aims to help children with conditions like cerebral palsy, neuromuscular diseases, or obesity improve their walking ability, strength, and overall quality of life. T…

This study is exploring whether adding immersive virtual reality (VR) to standard occupational therapy can help people with long-term upper limb pain. It will involve 12 participants who will use a VR device during their therapy sessions. The main goal is to see if VR improves ar…

This study aims to learn how a specific type of immune cell, called a monocyte, behaves in people with certain blood cancers. Researchers will collect blood samples from 70 participants who have not yet started treatment for their condition. By analyzing these cells, they hope to…

This study aims to discover biological markers that can predict which patients with certain blood cancers will respond well to standard first-line treatments. Researchers will analyze blood samples from 120 adults with polycythemia vera, essential thrombocythemia, or pre-myelofib…

This study is testing a new picture-based questionnaire called PETRA. It aims to better measure how often people with shoulder and arm pain avoid everyday tasks, like reaching or throwing. Researchers will give the questionnaire to 200 adults being evaluated for a specific type o…

This study aims to see if tracking the amount of a specific mutated gene (CALR) in the blood over time can help doctors predict when a patient's blood cancer might get worse. It will follow 260 adults with certain blood cancers that have this mutation for up to three years. The g…

This study aims to find out if the amount and type of gas a person passes after abdominal surgery can predict their risk of complications. Researchers will track 200 patients, having them record details about their gas and bowel movements before and after their operation. The goa…

This study aims to see if training emergency room doctors in how to announce an early miscarriage improves the psychological experience for patients. It will involve 1,000 women who experience a pregnancy loss before 14 weeks. The main goal is to measure if this specific communic…

This study aims to better understand a specific genetic mutation (ASXL1) found in a blood cancer called myelofibrosis. Researchers will observe 50 adult patients over 4 years to see how different patterns of this mutation relate to survival and the risk of the disease worsening. …

This study aims to understand a rare genetic disease called pseudoxanthoma elasticum (PXE) by looking at blood flow in the back of the eye. Researchers will compare detailed eye scans from 60 healthy volunteers to scans from 60 patients with PXE. The goal is to see if changes in …

This study aims to test a new, simpler questionnaire designed to measure how physically active people are. Researchers will compare answers from the new questionnaire with data from a wearable activity monitor worn by 118 participants from the general public. The goal is to see i…

This study aims to understand how common immediate food reactions are in children with eosinophilic esophagitis (EoE). Researchers will observe 40 children aged 6-18 who experience throat pain, pressure, or choking within minutes of eating certain foods. The goal is to gather inf…

This study aims to understand how Amyotrophic Lateral Sclerosis (ALS) affects social cognition—the ability to recognize emotions in faces and voices. Researchers will compare 74 French-speaking ALS patients to healthy volunteers using specific movie-based tests. The goal is to ga…

This study aims to understand if adding specific nutrients to blood cells can fix their energy production in patients with septic shock, a severe infection causing organ failure. Researchers will take blood samples from 55 patients in intensive care and test the cells in a lab. T…

This study aims to understand why women tend to have worse recovery and higher risk of heart failure after a heart attack compared to men. Researchers will follow 1,650 people for up to 10 years, using heart imaging scans to track how the heart's size and shape change over time. …

This study aims to understand how living in extreme isolation for long periods affects human health, specifically the immune system. Researchers will follow 9 healthy young adults spending a year at a remote French research station on the Kerguelen Islands. They will collect bloo…

This study aims to understand if and how a group of rare, inherited movement disorders called spinocerebellar ataxias (SCA) affect a person's social skills. Researchers will recruit 160 people, including patients with specific SCA types and healthy volunteers, to complete various…

This study aims to understand how two different types of ARDS (Acute Respiratory Distress Syndrome) affect how the lungs use oxygen when different pressure levels are set on a breathing machine. Researchers will observe 50 sedated patients on ventilators in France, using a specia…

This study aims to understand how chemotherapy affects memory, concentration, and thinking skills in people being treated for blood cancers like leukemia and lymphoma. Researchers will compare 120 cancer patients to a control group of their relatives, using questionnaires and thi…

This study aims to see if measuring the oxygen level in urine can help doctors predict when a critically ill patient in shock might develop kidney failure, or when their kidneys might start to recover. Researchers will enroll 55 patients in intensive care, some with shock and som…

This study aims to find early warning signs in children's blood that could predict if a rare brain inflammation disease (ADEM) will come back. Researchers will analyze blood samples from 20 children who have had their first attack. The goal is to understand the disease better and…