New device may beat drugs for dangerous lung clots

NCT ID NCT05111613

Completed Disease control Sponsor: Inari Medical Source: ClinicalTrials.gov ↗

First seen Nov 16, 2025 · Last updated May 15, 2026 · Updated 20 times

Summary

This study tested a device called FlowTriever that removes blood clots from the lungs, comparing it to standard clot-busting drugs. About 692 adults with acute pulmonary embolism (a serious lung clot) took part. The goal was to see if the device could lower the chance of death, bleeding, or needing intensive care. Results suggest the device may offer better outcomes than drugs alone.

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Contacts and locations

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Locations

AHN Saint Vincent Hospital

Erie, Pennsylvania, 16544, United States
Advocate Christ Medical Center

Oak Lawn, Illinois, 60453, United States
Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States
Ascension Alexian Brothers Medical Center

Elk Grove Village, Illinois, 60007, United States
Ascension Saint Thomas Hospital

Nashville, Tennessee, 37205, United States
Ascension St. Elizabeth Hospital

Appleton, Wisconsin, 54915, United States
Ascension St. John Hospital

Detroit, Michigan, 48236, United States
Ascension St. Vincent Hospital - Indianapolis

Indianapolis, Indiana, 46260, United States
Aurora St. Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Baptist Health South Florida

Miami, Florida, 33176, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Brigham and Womens Hospital

Boston, Massachusetts, 02115, United States
CentraCare St. Cloud Hospital

Saint Cloud, Minnesota, 56303, United States
Emory University

Atlanta, Georgia, 30322, United States
Gates Vascular Institute

Buffalo, New York, 14203, United States
Gundersen Health System

La Crosse, Wisconsin, 54601, United States
HCA Medical City Heart and Spine

Dallas, Texas, 75243, United States
HCA TriStar Centennial Medical Center

Nashville, Tennessee, 37203, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Herzzentrum Leipzig

Leipzig, Germany
Houston Methodist Hospital

Houston, Texas, 77030, United States
Huntington Hospital

Pasadena, California, 91105, United States
Inselspital - Universitätsspital Bern

Bern, 3010, Switzerland
Lexington Medical Center

West Columbia, South Carolina, 29169, United States
Loma Linda University Health

Loma Linda, California, 92354, United States
MUSC Health University Medical Center

Charleston, South Carolina, 29425, United States
Marien Hospital Wesel GmbH

Wesel, Germany
Memorial Hermann Medical Center

Houston, Texas, 77030, United States
Mercy Health West

Cincinnati, Ohio, 45211, United States
Methodist Main Hospital

San Antonio, Texas, 78229, United States
NewYork-Presbyterian Columbia University Irving Medical Center

New York, New York, 10032, United States
Northwell Health

Bay Shore, New York, 11706, United States
Norton Healthcare

Louisville, Kentucky, 40202, United States
Novant Health New Hanover Regional Medical Center

Wilmington, North Carolina, 28401, United States
OhioHealth Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Providence Sacred Heart Medical Center

Spokane, Washington, 99204, United States
Providence St. Joseph Orange

Orange, California, 92868, United States
Radiology and Imaging Associates

Lakeland, Florida, 33801, United States
Saint Louis University

St Louis, Missouri, 63104, United States
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Sarasota Memorial Hospital

Sarasota, Florida, 34239, United States
Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States
Spartanburg Regional Healthcare System

Spartanburg, South Carolina, 29303, United States
St. Luke's University Hospital

Bethlehem, Pennsylvania, 18015, United States
Summa Akron City Hospital

Akron, Ohio, 44304, United States
Tallahassee Memorial Hospital

Tallahassee, Florida, 32308, United States
Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19108, United States
UPMC Harrisburg

Harrisburg, Pennsylvania, 17101, United States
UPMC Presbyterian

Pittsburgh, Pennsylvania, 19140, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
University of North Carolina Health

Chapel Hill, North Carolina, 27514, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
University of Rochester Medical Center

Rochester, New York, 14642, United States
University of South Florida Tampa General Hospital

Tampa, Florida, 33606, United States
Universtitaetsklinikum Dusseldorf

Düsseldorf, Germany
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Virtua Lourdes

Camden, New Jersey, 08103, United States

Conditions

Explore the condition pages connected to this study.

PULMONARY EMBOLISM PULMONARY THROMBOEMBOLISM