PULMONARY EMBOLISM

This study compares two treatments for serious lung blood clots (pulmonary embolism). Researchers want to see if adding a special ultrasound device to standard blood thinners works better than blood thinners alone. The device delivers clot-dissolving medicine directly to the clot…

This study is testing a medical device called the Vertex Pulmonary Embolectomy System to see if it can safely remove blood clots from the lungs of people with a serious type of pulmonary embolism. The device is inserted into blood vessels to physically pull out the clots, aiming …

This study is testing if a personalized starting dose for the blood thinner heparin works better than the standard one-size-fits-all approach. It involves 145 adults being treated for blood clots or certain heart conditions. Researchers will see if using a formula based on a pati…

This study is testing a new, lower-dose treatment for serious blood clots in the lungs (pulmonary embolism). Doctors use a special catheter with ultrasound to deliver a clot-busting drug directly to the clots. The goal is to clear the clots and help the heart recover while trying…

This study is testing if a new monthly injection (abelacimab) works better and is safer than a standard daily injection (dalteparin) for preventing dangerous blood clots from coming back. It is for adults with specific cancers of the stomach, intestines, or urinary system who hav…

This study is testing a new medical device called the Aventus Thrombectomy System. It is designed to physically remove dangerous blood clots from the lungs of patients with a sudden, severe pulmonary embolism. The trial will enroll 130 adults to see if the procedure is safe and e…

This study compares two non-invasive methods to help patients with dangerous lung clots breathe better. It tests whether a comfortable nasal tube (HFNC) works as well as or better than a traditional face mask ventilator (NIV) at helping patients breathe on their own and survive. …

This study aims to find the best personalized treatment plan for people who have had their first dangerous blood clot (like a deep vein thrombosis or pulmonary embolism). Researchers will use a simple cheek swab and questionnaire to estimate each patient's risk of having another …

This study aims to understand what causes dangerous blood clots in the lungs (pulmonary embolism) and legs (deep vein thrombosis). Researchers are following over 21,000 African American and white adults who were already part of two large heart health studies. They are collecting …

This study aimed to understand if a gas called inhaled nitric oxide (iNO) could help improve heart and lung function in patients with serious, life-threatening blood clots in the lungs (pulmonary embolism). It planned to enroll about 20 patients at UCLA Medical Center and measure…

This study aimed to test if a non-invasive finger-cuff device could safely and effectively monitor heart function in real-time for patients hospitalized with serious pulmonary embolism (a dangerous lung blood clot). The goal was to see if the device's readings could help doctors …

This study aims to understand why some young people have trouble breathing and exercising after their first serious blood clot in the leg or lung. Researchers will follow 115 participants, aged 8 to 21, for a year, measuring their heart, lung, and muscle function during exercise …