PULMONARY EMBOLISM

This study compares two treatments for people with a serious type of blood clot in the lungs (pulmonary embolism). Half of the 544 participants will receive standard blood thinners, while the other half will get blood thinners plus a special device that uses ultrasound to help di…

This study tests a new way to treat pulmonary embolism (blood clots in the lungs) using a low dose of clot-busting medicine delivered through a thin tube guided by ultrasound. About 60 adults with moderate to severe clots will receive this treatment to see if it safely improves b…

This study aims to find the best length of time for people to take blood thinners after their first blood clot (in the leg or lung). Instead of a standard duration, researchers use a questionnaire and cheek swab to estimate each person's risk of another clot versus bleeding. Base…

This study tests a new device called the Aventus Thrombectomy System to safely remove blood clots from the lungs in people with a sudden, severe pulmonary embolism. About 130 adults aged 18 to 80 with symptoms lasting less than two weeks will be enrolled. The goal is to see if th…

This study tests whether using a patient's gender, weight, and kidney function to calculate the first dose of the blood thinner heparin helps reach the right level faster than a standard dose based only on weight. About 145 adults with conditions like deep vein thrombosis, pulmon…

This study tests a device that removes blood clots from the lungs of people with acute pulmonary embolism. About 125 adults with recent symptoms and evidence of heart strain will be enrolled. The goal is to see if the procedure safely improves heart function and reduces serious c…

This study compares two non-invasive breathing support methods—high-flow nasal cannula and non-invasive ventilation—for people with acute respiratory failure caused by a pulmonary embolism (blood clot in the lungs). The goal is to see which method helps patients breathe on their …

This study looks at what causes dangerous blood clots in the legs (venous thrombosis) and lungs (pulmonary embolism) by following over 21,000 African American and white adults from two large health studies. Researchers are tracking participants over time to find patterns and risk…

This study follows children and teens who had a first-time blood clot in their leg or lung to understand why they may have trouble exercising or feel short of breath. Researchers will measure their oxygen use during exercise and use heart scans to look for changes. The goal is to…

This study aims to find genetic markers that may increase the risk of a pulmonary embolism (a serious blood clot in the lung) after total hip or knee replacement surgery. Researchers will collect blood samples from 100 adults aged 18-70 who have had a pulmonary embolism after suc…

This study aimed to see if breathing in nitric oxide gas could improve blood flow in the lungs of people with a serious pulmonary embolism (a blood clot in the lung). It planned to include 20 adults at one hospital, measuring heart and lung pressures before, during, and after the…

This study aimed to see if a non-invasive blood pressure monitor could help doctors assess risk and treatment response in people with a pulmonary embolism (a blood clot in the lungs). The researchers planned to measure how well the heart pumps blood in real time using a finger cu…