New Clot-Busting device could save lives in pulmonary embolism

NCT ID NCT05907564

Ongoing Disease control Sponsor: Inquis Medical, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial is testing a device called the Aventus Thrombectomy System, which suctions out blood clots from the lungs in people with acute pulmonary embolism. The study involves 130 participants aged 18 to 80. The goal is to see if the device is safe and effective at improving blood flow and reducing major complications like death or bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Aventus Thrombectomy System (a device that suctions out blood clots from the lungs)

What this could lead to

If it works, this could offer a safer, faster way to remove dangerous blood clots from the lungs, potentially reducing death and serious complications.

What could go wrong

This is an early-stage study with only 130 participants, so results may not apply to everyone. Risks include bleeding, vessel injury, or the device not working as expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cardiovascular disorder Embolism Embolism and Thrombosis lung disorder pulmonary embolism respiratory system disorder Thromboembolism vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES EMBOLISM EMBOLISM AND THROMBOSIS LUNG DISEASES PULMONARY EMBOLISM RESPIRATORY TRACT DISEASES VASCULAR DISEASES

Contacts and locations

Show contact details

Locations

Alexian Brothers Medical Center

Elk Grove Village, Illinois, 60007, United States
Ascension Providence

Southfield, Michigan, 48075, United States
Ascension Seton

Austin, Texas, 78705, United States
Ascension St. John

Tulsa, Oklahoma, 74006, United States
Ascension St. Vincent

Indianapolis, Indiana, 46260, United States
Centennial Medical Center (HCA)

Nashville, Tennessee, 37203, United States
CentraCare Heart and Vascular

Saint Cloud, Minnesota, 56303, United States
El Camino Health

Mountain View, California, 94040, United States
Emory University

Atlanta, Georgia, 30322, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Holy Name Medical Center

Teaneck, New Jersey, 07666, United States
Honor Health

Scottsdale, Arizona, 85258, United States
Ichan School of Medicine at Mount Sinai

New York, New York, 10019, United States
McLaren Health Care

Bay City, Michigan, 48708, United States
Medstar

Washington D.C., District of Columbia, 20010, United States
MemorialCare

Long Beach, California, 90806, United States
NorthBay Medical Center

Fairfield, California, 94533, United States
Northwestern University

Chicago, Illinois, 60611, United States
Ochsner Health

New Orleans, Louisiana, 70121, United States
OhioHealth Research Institute

Columbus, Ohio, 43214, United States
ProMedica - Jobst Vascular

Toledo, Ohio, 43606, United States
Sutter Health

Sacramento, California, 95816, United States
The Miriam Hospital

Providence, Rhode Island, 02906, United States
University Hospitals

Cleveland, Ohio, 44106, United States