New device aims to improve survival and reduce hospital stays for lung clot patients

NCT ID NCT06055920

Ongoing Disease control Sponsor: Inari Medical Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 4 times

Summary

This study compares a device called FlowTriever (used with blood thinners) to blood thinners alone for people with intermediate-risk pulmonary embolism (blood clots in the lungs). About 1,200 adults with clots in major lung arteries and signs of heart strain will be randomly assigned to one of two groups. The goal is to see if the device reduces death, worsening symptoms, hospital readmission, and shortness of breath within 30 days.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY EMBOLISM

Contacts and locations

Locations

AHN Saint Vincent Hospital

Erie, Pennsylvania, 16505, United States
AP-HM Hopital La Timone

Marseille, France
Aarhus University Hospital

Aarhus, 8200, Denmark
AdventHealth Orlando

Orlando, Florida, 32803, United States
Allegheny Health Network Research Institute

Pittsburgh, Pennsylvania, 15212, United States
Ascension Saint Thomas Hospital

Nashville, Tennessee, 37203, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Baylor Scott & White - Temple

Temple, Texas, 76508, United States
Brookwood Medical Center

Birmingham, Alabama, 35243, United States
CCB Frankfurt

Frankfurt, Germany
CHU Lille

Lille, France
Charité Campus Virchow Clinic - Klinik fuer Radiologie

Berlin, Germany
Charleston Area Medical Center

Charleston, West Virginia, 25304, United States
Elisabeth Hospital GmbH

Essen, Germany
Emory University

Atlanta, Georgia, 30322, United States
HCA FL Largo Medical Center

Largo, Florida, 33770, United States
HCA Tristar

Brentwood, Tennessee, 37027, United States
Helios Kliniken Schwerin

Schwerin, Germany
HerzZentrum Dresden Universitaetsklinik

Dresden, Germany
Hopital Clinico Universitario San Carlos

Madrid, Spain
Huntington Memorial Hospital

Pasadena, California, 91105, United States
Hôpital Louis Pradel

Lyon, France
Hôpital Nord Marseille

Marseille, France
Inova Fairfax

Falls Church, Virginia, 22042, United States
Jamaica Hospital

Queens, New York, 11418, United States
John Paul II Hospital

Krakow, Poland
Klinikum rechts der Isar (TUM)

Munich, Germany
Ludwig Maximilians-University

Munich, Germany
Luzerner Kantonsspital

Lucerne, Switzerland
McLaren Greater Lansing

Lansing, Michigan, 48910, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Methodist Main Hospital

San Antonio, Texas, 78229, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
Nebraska Medical Center

Omaha, Nebraska, 68105, United States
Northwell Health

New York, New York, 10075, United States
Northwestern University

Chicago, Illinois, 60611, United States
Ohio State University - Wexner Medical Center

Columbus, Ohio, 43210, United States
Onze Lieve Vrouwziekenhuis

Aalst, Belgium
Parkland Hospital

Dallas, Texas, 75235, United States
Royal Columbian Hospital

New Westminster, British Columbia, V3L 3W7, Canada
SUNY, The University of Buffalo/Gates Vascular

Buffalo, New York, 14203, United States
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Schwarzwald-Baar-Klinikum

Villingen-Schwenningen, Germany
Sentara Vascular Specialists

Norfolk, Virginia, 23507, United States
St. Luke's University Hospital

Bethlehem, Pennsylvania, 18015, United States
Stony Brook University Hospital

Stony Brook, New York, 11794, United States
Surrey Memorial Hospital

Surrey, British Columbia, V3V 1Z2, Canada
Texas Health Harris Methodist Hospital

Fort Worth, Texas, 76104, United States
The Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
The University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Thomas Jefferson University

Philadelphia, Pennsylvania, 19144, United States
UAB Division of Cardiovascular Disease

Birmingham, Alabama, 35205, United States
UPMC Hamot

Erie, Pennsylvania, 16507, United States
UPMC Harrisburg

Harrisburg, Pennsylvania, 17101, United States
UPMC Heart and Vascular Institute

Pittsburgh, Pennsylvania, 15213, United States
UTMC Knoxville

Knoxville, Tennessee, 37920, United States
Unfall Krankenhaus Berlin

Berlin, Germany
Universitaetsklinikum Dὒsseldorf

Düsseldorf, Germany
Universitaetsklinikum Essen

Essen, Germany
Universitaetsklinikum Hamburg Eppendorf

Hamburg, Germany
Universitaetsspital Basel

Basel, Switzerland
University Hospital - Heidelberg

Heidelberg, Germany
University Hospital Augsburg

Augsburg, Germany
University Hospital Cologne

Cologne, Germany
University Hospital Regensburg

Regensburg, Germany
University of Cincinnati Medical Center

Cincinnati, Ohio, 45219, United States
University of Colorado, Denver

Aurora, Colorado, 80045, United States
University of Rochester Medical Center

Rochester, New York, 14642, United States
University of Washington

Seattle, Washington, 98195, United States
Universitäts-Herzzentrum Bad Krozingen

Bad Krozingen, Germany
Universitätsspital Bern

Bern, Switzerland
Vancouver General Hospital

Vancouver, British Columbia, V5Z 1M9, Canada
Virtua Health

Camden, New Jersey, 08103, United States
Wellspan York Hospital

York, Pennsylvania, 17403, United States
West Virginia University Ruby Memorial Hospital

Morgantown, West Virginia, 26506, United States
Westpfalz Klinikum

Kaiserslautern, Germany
Yale University

New Haven, Connecticut, 06520, United States

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