New Ultrasound-Guided clot treatment aims to save lungs and hearts
NCT ID NCT06310018
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a procedure that uses ultrasound and a catheter to deliver a low dose of a clot-dissolving drug directly to blood clots in the lungs. The goal is to quickly reduce the strain on the heart and improve blood flow, while keeping the risk of serious bleeding low. The trial includes 60 adults with severe but stable pulmonary embolism and signs of heart stress.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tissue plasminogen activator (tPA) - a clot-dissolving drug
What this could lead to
If successful, this could offer a safer, lower-dose way to treat dangerous blood clots in the lungs, reducing heart strain and bleeding complications.
What could go wrong
This is an early, single-arm study with only 60 participants, so results may not apply broadly. The trial is currently suspended, and bleeding risks remain a concern.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PULMONARY EMBOLISM are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States