One-Size-Fits-No-One: tailored clot prevention after first blood clot

NCT ID NCT06087952

First seen Feb 22, 2026 · Last updated May 14, 2026 · Updated 8 times

Summary

This study aims to find the best length of time for people to take blood thinners after their first blood clot (in the leg or lung). Instead of a standard duration, researchers use a questionnaire and cheek swab to estimate each person's risk of another clot versus bleeding. Based on these risks, a personalized treatment plan is given, and some participants are randomly assigned to different strategies. The goal is to prevent future clots while avoiding unnecessary bleeding risks.

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Contacts and locations

Locations

  • Admiraal de Ruyter Ziekenhuis

    Goes, Netherlands

  • Amphia Ziekenhuis

    Breda, Netherlands

  • Amsterdam Medical Center, location AMC

    Amsterdam, Netherlands

  • Catharina Ziekenhuis

    Eindhoven, Netherlands

  • Deventer Ziekenhuis

    Deventer, Netherlands

  • Diakonessenhuis

    Utrecht, Netherlands

  • Groene Hart Ziekenhuis

    Gouda, Netherlands

  • Haaglanden Medisch Centrum

    The Hague, Netherlands

  • HagaZiekenhuis

    The Hague, Netherlands

  • Ikazia Ziekenhuis

    Rotterdam, Netherlands

  • Isala Klinieken

    Zwolle, Netherlands

  • Leiden University Medical Center

    Leiden, South Holland, 2333 ZA, Netherlands

  • Martini Ziekenhuis

    Groningen, Netherlands

  • Nij Smellinghe Ziekenhuis

    Drachten, Netherlands

  • Radboud University Medical Center

    Nijmegen, Netherlands

  • Rode Kruis Ziekenhuis

    Beverwijk, Netherlands

  • University Medical Center Groningen

    Groningen, Netherlands

  • Wilhelmina Ziekenhuis

    Assen, Netherlands

  • Ziekenhuis Gelderse Vallei

    Ede, Netherlands

Conditions

Explore the condition pages connected to this study.