NEUROPATHIC PAIN

This study tested if a new combination of a nerve-supporting supplement (Nucleo CMP) and a B-vitamin complex (Neurorubine) could provide better and longer-lasting pain control for trigeminal neuralgia, a severe facial pain condition, compared to the standard medication carbamazep…

This small, completed study explored whether adding psychotherapy to ketamine treatment helps make pain relief last longer for people with chronic nerve pain. Thirty adults with moderate-to-severe nerve pain were randomly assigned to receive either ketamine, psychotherapy, or a c…

This study tested whether various health and wellness products sold directly to consumers could help reduce pain. Over 2,000 adults in the US who wanted less pain took part from home over 7 weeks. Participants received either an active product or a placebo (a look-alike with no a…

This study tested a one-time class designed to teach pain science and coping skills to youth (ages 10-18) with chronic pain. The goal was to see if the class was practical to run and acceptable to young participants. Researchers also checked if the class might help reduce how muc…

This study tested whether a wearable device that plays specific light and sound patterns could help reduce chronic nerve pain. Seventy-five adults with neuropathic pain used the device at home for 8-14 weeks. Researchers compared the real device to a fake one to see if it improve…

This study tested whether a non-invasive brain stimulation technique could reduce pain in people with chronic low back pain. Thirty adults with neuropathic pain received magnetic pulses targeted at a specific brain area. Researchers measured changes in pain levels and a specific …

This study tested whether acupuncture, a traditional needle-based therapy, could help reduce severe foot and leg pain caused by nerve damage in people living with HIV. Nearly 200 participants were randomly assigned to receive either real acupuncture, a fake version, or no treatme…

This study tested whether a gentle, non-invasive electrical brain stimulation could reduce chronic nerve pain. It involved 24 people, including both healthy volunteers and patients with long-term, treatment-resistant pain. Researchers compared the effects of real stimulation to a…

This study tested whether a therapy using special prism goggles could help reduce pain and improve function in people with Complex Regional Pain Syndrome (CRPS), a severe and often chronic pain condition that can develop after an injury like a fracture. Fifty-four patients with r…

This study aimed to find out if a specific, low-level setting on an implanted nerve stimulator provides real pain relief, or if the benefit is just a placebo effect. It involved 20 adults with chronic nerve pain who already had the device and were getting good results. Researcher…

This study tested if a single nerve-block injection given during mastectomy surgery could reduce both immediate post-surgery pain and the risk of developing long-term chronic pain. Researchers compared two groups of patients: one received the nerve block, and the other did not. T…

This study looked at whether medical cannabis could help reduce nerve pain and inflammation in people living with HIV. Researchers followed 35 adults with HIV and nerve pain who were already certified for medical cannabis use. Over 14 weeks, they compared how different ratios of …

This study explored ways to make nerve stimulation treatments more accessible to Black and Hispanic patients with chronic nerve pain. Researchers tested whether culturally sensitive educational videos could improve understanding and expectations about these treatments. The study …

This study followed over 2,300 adults in Chile for one year to understand how common chronic pain is and how it connects to mental health, loneliness, and work stress. Researchers called participants to track their pain levels, mood, sleep, and daily life impact over 12 months. T…

This study aimed to understand how spinal cord stimulation devices affect pain processing in people with chronic pain. Researchers observed 34 patients who were already using these devices as part of their regular medical care. They measured how repeated pain signals built up ove…

This study aimed to understand if people with neck-related headaches have a more sensitive nervous system and nerve pain compared to healthy people. Researchers compared 72 adults, half with these specific headaches and half without, using questionnaires about pain, sleep, and mo…

This study aimed to understand how a non-invasive brain stimulation treatment changes brain activity in people with chronic nerve pain. Researchers compared brain scans and measurements from 65 healthy volunteers and chronic pain patients before and after receiving magnetic brain…

This study looked back at medical records to see if a common medication for nerve pain (pregabalin) affects levels of vitamin B12 and folic acid in the body. Researchers checked the vitamin levels of 96 patients before and after they started the medication. The goal was to gather…

This study aimed to find early signs that could predict which shingles patients would develop long-lasting nerve pain called postherpetic neuralgia (PHN). Researchers followed 151 adults with shingles for 3 months, collecting detailed health information and blood samples to look …