NEUROPATHIC PAIN

This study tests whether a gentle brain stimulation technique called tDCS, combined with standard rehabilitation, can prevent the development of chronic pain after a stroke. Researchers will enroll 60 stroke survivors who are at high risk for pain and give half of them real stimu…

This study looks at a new way to treat cervical radiculopathy, a condition causing neck and arm pain from a pinched nerve. Since some people can't tolerate direct treatment on their painful arm, researchers will test if gently moving the opposite arm can provide relief. Forty adu…

This study looks at whether aromatherapy foot massage can reduce nerve pain in people with type 2 diabetes. About 78 adults will give themselves a 10-minute foot massage three times a week for four weeks, using either a special oil or a plain oil. Researchers will check pain leve…

This early-stage study tests whether a new drug called ASCT-83 is safe and how the body processes it. It involves 72 healthy adults who will receive either the drug or a placebo. The results will help determine safe doses for future studies in people with nerve pain.

This early study tests a brain stimulation technique for people with long-term nerve pain that hasn't responded to other treatments. About 20 adults will receive a surgically placed device to stimulate specific brain networks. The main goal is to see if the procedure is feasible …

This study tests a device called Scrambler Therapy to see if it can safely reduce nerve pain in children with cancer that has spread to the bone. About 70 children will receive the non-invasive treatment, and researchers will measure changes in pain intensity and medication use. …

This study tests a wearable ultrasound device that targets nerves to reduce chronic pain without medication or surgery. About 90 adults with nerve-related pain will attend a single visit to receive ultrasound stimulation and report their pain levels. The goal is to see if the dev…

This study tests whether giving pain-relief procedures—like nerve blocks—at home can help adults with chronic, cancer, or nerve pain. About 100 people in a home hospital program will receive ultrasound-guided treatments at home instead of in a clinic. The goal is to see if this a…

This small study tests a new way to treat nerve pain after spinal cord injury. Ten people will try a combination of virtual reality walking, muscle vibration, and mild brain stimulation over ten sessions. The goal is to see if this approach lowers pain and improves daily life, an…

This study tests an injectable supplement (Epinosine B Forte) containing ATP and B vitamins to see if it reduces nerve pain, numbness, and tingling in people with diabetic neuropathy. About 200 adults with diabetes and nerve symptoms will receive either the study supplement or an…

This early-phase study tests whether a diabetes drug called glibenclamide (glyburide) can safely reduce nerve pain in people with multiple sclerosis. Ten adults with MS and neuropathic pain will take the oral extended-release drug, and researchers will monitor safety, drug levels…

This study looks at whether early ultrasound scans of burn scars can predict which patients will have lasting pain 3 to 6 months after injury. Researchers will measure scar thickness, blood flow, and nerve involvement in 150 adults with blast- or drone-related burns. The goal is …

This study looks at 180 adults getting a pacemaker or defibrillator for the first time. Researchers will track pain and quality of life for a year, then use that data to build an AI system that predicts who is at risk for long-term pain. The goal is to help doctors prevent chroni…

This study creates a large international registry to collect real-world data on spinal cord stimulation and other neuromodulation therapies for people with neuropathic pain. Researchers will track patient outcomes, device safety, and treatment effectiveness across clinics in mult…

This study looks at spinal cord swelling after a procedure called cordotomy, which is used to treat severe cancer pain. Researchers will use MRI scans to measure swelling and compare it to patients' pain levels and other symptoms. The goal is to better understand how these change…