Cure My Disease

Don't miss your cure!

 Log in / Sign up

Numbing patch may stop chronic pain after osteoporosis fractures

NCT ID NCT07691359

Prevention Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests whether applying a 5% lidocaine plaster daily for two months can prevent chronic nerve pain after an osteoporotic vertebral fracture. Participants aged 50 and older with a recent fracture and moderate pain are randomly assigned to receive the plaster plus standard care or standard care alone. The study measures how many develop nerve pain at two months using a questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
5% lidocaine plaster
What this could lead to
If it works, this could point toward a simple, non-drug way to prevent chronic nerve pain after spinal fractures in older adults.
What could go wrong
This is a small, early proof-of-concept trial with only 30 participants, so results may not be generalizable. The plaster may not prevent pain, and skin irritation is possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female participant aged 50 years or older. * Diagnosis of osteoporosis established by the treating rheumatologist. * Osteoporotic vertebral fracture diagnosed within the previous month. * Pain intensity of ≥3 on a numerical rating scale at the fracture site. * Able and willing to provide written informed consent. * Affiliated with a French health insurance system. Exclusion Criteria: * Medical or surgical condition considered by the investigator to be incompatible with study participation. * Known hypersensitivity to lidocaine, any excipient of the study treatment, or other amide-type local anesthetics. * Current treatment with Class I antiarrhythmic agents (e.g., tocainide, mexiletine) or other local anesthetics. * Inflamed or damaged skin at the intended application site (e.g., active herpes zoster lesions, dermatitis, or wounds). * Pregnant or breastfeeding women. * Women of childbearing potential not using an effective contraceptive method. * Positive urine pregnancy test for women whose menopausal status cannot be confirmed. * Participation in another clinical research study. * Individuals under legal protection or deprived of liberty. * Refusal to participate.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Neuropathic pain are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteoporosis neuralgia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuropathic pain Osteoporotic vertebral fracture

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.