Numbing patch may stop chronic pain after osteoporosis fractures

NCT ID NCT07691359

Not yet recruiting Prevention Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests whether applying a 5% lidocaine plaster daily for two months can prevent chronic nerve pain after an osteoporotic vertebral fracture. Participants aged 50 and older with a recent fracture and moderate pain are randomly assigned to receive the plaster plus standard care or standard care alone. The study measures how many develop nerve pain at two months using a questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 5% lidocaine plaster
What this could lead to: If it works, this could point toward a simple, non-drug way to prevent chronic nerve pain after spinal fractures in older adults.
What could go wrong: This is a small, early proof-of-concept trial with only 30 participants, so results may not be generalizable. The plaster may not prevent pain, and skin irritation is possible.

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Conditions

The condition(s) this trial relates to.

osteoporosis neuralgia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROPATHIC PAIN OSTEOPOROTIC VERTEBRAL FRACTURE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CHU Clermont-Ferrand

Clermont-Ferrand, 63000, France

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