Could a new drug ease nerve pain in a rare disease?

NCT ID NCT07699770

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial investigates whether the drug crisugabalin can reduce neuropathic pain in people with neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune condition affecting the nerves. Participants will receive either crisugabalin or a placebo, and their pain levels will be tracked using a standard rating scale. The study aims to see if crisugabalin offers meaningful pain relief for this specific group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
crisugabalin
What this could lead to
If it works, this could provide a new option for managing chronic pain in NMOSD, improving quality of life.
What could go wrong
This is an early exploratory trial with a small number of participants, so results may not be conclusive or apply to everyone. Side effects of crisugabalin are not yet fully known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inner Mongolia People's Hospital

    Hohhot, Inner Mongolia, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tangdu Hospotal

    Xi'an, Shaanxi, China

    Contact Phone: •••-•••-••••

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Harbin Medical University

    Harbin, Heilongjiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of China Medical University

    Shenyang, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Jilin University

    Changchun, Jinlin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xinjiang Uygur Autonomous Region People's Hospital

    Ürümqi, Xinjiang Uygur Autonomous Region, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • the First Hospital of Tsinghua University

    Beijing, Chaoyang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Other studies related to the condition(s) this trial covers.