NEUROPATHIC PAIN

This study looks at how well a closed-loop spinal cord stimulator works for people with long-term pain. Researchers will track pain levels and quality of life in 25 adults who have had pain for at least 6 months. The device automatically adjusts stimulation to help reduce pain.

This study looks at whether taking vitamin D supplements can lessen nerve pain caused by taxane chemotherapy. About 120 people with low vitamin D levels who are starting chemo will be randomly assigned to get vitamin D or standard care. The goal is to see if vitamin D helps reduc…

This study planned to test whether photobiomodulation (a type of light therapy) could reduce nerve pain and improve feeling in one woman after mastectomy. The treatment would have been given for 6 weeks, measuring pain, sensation, strength, and quality of life. However, the study…

This study tests a new drug (LY3848575) for people with long-term nerve pain starting in the feet and moving up to just below the knee. About 558 adults will receive either the drug or a placebo to see if it safely reduces pain and improves sleep and daily activities. Participati…

This study looks at whether adding a muscle stimulation program twice a day can further reduce pain and improve quality of life for people with chronic back pain who already use a spinal cord stimulator. About 60 adults who have had their stimulator implanted for up to 5 years wi…

This study tests whether a spinal cord stimulator (BurstDR) can reduce chronic pain in people with diabetic neuropathy. Twenty adults with long-lasting, severe leg pain who haven't gotten relief from standard medicines will try a temporary stimulator for one week. If their pain d…

This study tests whether a noninvasive electrical stimulation device placed on the back can reduce nerve pain and improve quality of life. Sixty-two adults with chronic nerve pain will receive either real or sham stimulation during a hospital stay, with follow-up for 3 months. Re…

This study planned to look at brain wave patterns (EEG) in adults with chronic nerve pain who were already scheduled to receive ketamine infusions. The goal was to see if certain brain signals could predict how well ketamine works for pain and mood. However, the study was withdra…

This study looks at how common nerve-related eye pain is in people who feel discomfort in their eyes. Researchers will test 1,000 participants to see if their pain is linked to nerve issues rather than typical dry eye. The goal is to better understand these conditions, not to tes…

This study looks at how the nervous system becomes extra sensitive in people with different kinds of long-term pain. Researchers will use surveys, thinking tests, and brain wave measurements to compare pain types. About 185 adults with chronic pain will be checked at the start an…

This study looks at how common nerve-related pain is in people with knee osteoarthritis and whether it's linked to night pain. Researchers will ask 150 participants about their pain and sleep quality. The goal is to better understand these connections, not to test a new treatment…