Could a seizure drug ease nerve pain in spinal cord injury?
NCT ID NCT05639946
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 3 trial tested whether brivaracetam, a drug used for seizures, can reduce chronic nerve pain in people with spinal cord injury. 44 adults with persistent pain took part. The study compared brivaracetam to a placebo and measured changes in pain intensity and daily interference over 7 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- brivaracetam
- What this could lead to
- If it works, this could offer a new medication option for people with spinal cord injury who suffer from hard-to-treat nerve pain.
- What could go wrong
- This is a small, early-phase trial with only 44 participants. The drug may not reduce pain better than a placebo, and side effects like drowsiness are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Minnesota
Minneapolis, Minnesota, 55455, United States
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Other studies related to the condition(s) this trial covers.
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