COGNITIVE DYSFUNCTION

This study involved 1,539 participants and aimed to develop an artificial intelligence platform that screens for cognitive dysfunction by analyzing eye movements. The platform also provides referral suggestions based on the screening results. The goal was to see how accurately th…

This study looked at whether a home-based physical activity program and computer-based cognitive training, alone or together, could prevent memory loss in older women with heart disease. 253 women aged 65 and older with cardiovascular disease but no regular exercise or cognitive …

This study tested a non-drug training program for people with mild to moderate Alzheimer's disease. The training used personal photos and videos to help participants better recognize time, place, and people. 126 older adults took part, with some receiving the training three times…

This study tested a 12-week intensive aerobic and resistance exercise program in 58 adults aged 40-85 with type 2 diabetes and mild cognitive issues. Researchers measured changes in thinking skills, blood sugar, inflammation, and physical function. The goal was to see if exercise…

This study tested a special exercise program that combines turning movements with thinking tasks to help people with diabetic nerve damage. Fifty adults aged 50 and older with mild balance and thinking problems took part. The goal was to see if this training could improve their b…

This study tested whether a special magnetic device, used at home, could help people with long COVID who have trouble thinking clearly (brain fog). Thirty adults used the device for 4 weeks and were then followed for another 4 weeks. The main goal was to see if the device was eas…

This study tested whether a program combining cognitive behavioral therapy, cognitive rehabilitation, and lifestyle coaching is practical and helpful for people with mild cognitive impairment, traumatic brain injury, multiple sclerosis, or long COVID. Fifteen participants receive…

This study tested a new exercise device called FitMi AD in 31 people with mild cognitive impairment or mild dementia from Alzheimer's. The device uses sensors to track movements while users follow exercises shown on a computer screen. Researchers measured improvements in balance,…

This study tested whether adding structured supportive psychotherapy to the antipsychotic risperidone helps improve cognitive function and reduce inflammation in people with schizophrenia. Forty-six men with early-stage schizophrenia took part. Half received risperidone plus 12 s…

This study tested a drug called SAGE-718 in 26 people with mild memory loss or early Alzheimer's. The main goal was to see if the drug is safe and tolerable, and to check if it helps with thinking, memory, or mood. Participants took the drug and were monitored for side effects an…

This study tested an experimental drug called SAGE-718 to see if it could improve thinking and memory in people with Parkinson's disease who have mild cognitive impairment. 86 participants took either the drug or a placebo. The main goal was to measure changes in processing speed…

This study tested whether a noninvasive brain stimulation technique called repetitive Transcranial Magnetic Stimulation (rTMS) could improve memory in people with mild cognitive impairment (MCI). 69 participants were randomly assigned to receive active rTMS to one of two brain ar…

This study tested whether a procedure called a stellate ganglion block (SGB), given with standard medication, could improve thinking and memory in people with Alzheimer's disease. Forty participants were randomly assigned to receive either SGB plus standard drugs or standard drug…

This study tested whether digital or physical brain games can improve thinking, mood, and quality of life in 514 older adults with mild-to-moderate Alzheimer's disease. Participants did one-on-one cognitive stimulation activities, either on a computer or with traditional material…

This study tested a new medicine called SAGE-718 in 18 people with Parkinson's disease who also have mild memory or thinking problems. The main goal was to see if the drug is safe and tolerable, and to check if it helps with thinking, mood, and movement. The study was completed a…

This study tested whether an 8-week mindfulness program could reduce anxiety in older adults (60+) who worry about their memory but still score normally on memory tests. 168 participants were randomly assigned to either mindfulness training or a health education class. The goal w…

This study looked at whether continuously measuring oxygen levels in the brain during heart surgery can help prevent memory or thinking problems afterward. It included 326 older adults having planned coronary bypass surgery. Researchers compared standard care to care guided by a …

This study placed 15 healthy adults in an underground cave for 40 days with no clocks or natural light. Researchers measured how the group's sense of time, sleep patterns, thinking skills, and teamwork changed in this extreme environment. The goal was to understand how humans ada…

This study looked at whether a 30-minute walk outside in a green area helps people recover from mental tiredness and stress better than walking on a treadmill indoors. Researchers split 80 healthy young adults into two groups: one walked outdoors in nature, the other walked on a …

This study tested whether using EEG brain-wave monitoring during general anesthesia helps doctors give just the right amount of medicine. The goal was to see if this approach reduces drug use, shortens time to wake up after surgery, and lowers the risk of short-term thinking prob…

This study looked at 102 adults having planned heart surgery to see if drops in brain oxygen levels during the operation are linked to memory or thinking problems afterward. Researchers measured brain oxygen with a special monitor and tested thinking skills before and after surge…

This study looked at 134 adults with chronic sinusitis to see if sleep problems and daytime tiredness predict worse thinking skills and quality of life. Participants filled out questionnaires about their symptoms and daily functioning. The goal was to better understand how sinusi…

This study looked at whether shining a special light on the head (called transcranial photobiomodulation) can improve blood flow in the brain and help with thinking skills. Researchers tested 24 adults aged 18 to 80. The goal was to see if this light therapy could be a simple way…