Talk therapy boosts brain power in schizophrenia patients, study suggests

NCT ID NCT07477301

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding structured supportive psychotherapy to the antipsychotic drug risperidone helps improve thinking and reduce inflammation in people with schizophrenia. Forty-six male patients were split into two groups: one received risperidone plus 12 therapy sessions over 6 weeks, the other received risperidone alone. Researchers measured cognitive function and a blood marker of inflammation before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

supportive psychotherapy

What this could lead to

If it works, this could point toward a simple, low-cost addition to medication that helps people with schizophrenia think more clearly and reduces inflammation.

What could go wrong

This is a small, early-phase trial with only 46 male patients from one ethnic group, so results may not apply to everyone. The study was also registered after completion, which can introduce bias.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction Inflammation inflammatory disease schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dadi Psychiatric Hospital

    Makassar, South Sulawesi, 90245, Indonesia