COGNITIVE DYSFUNCTION
Clinical trials for COGNITIVE DYSFUNCTION explained in plain language.
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New drug trial targets dual brain proteins to slow lewy body dementia
Disease control Not yet recruitingThis study tests whether the drug donanemab can slow down worsening of thinking and daily living skills in people with early cognitive decline who also have signs of Lewy body dementia and Alzheimer's-related brain changes. About 350 participants will receive either donanemab or …
Matched conditions: COGNITIVE DYSFUNCTION
Phase: PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 17, 2026 00:28 UTC
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Eye scan could spot Alzheimer's before symptoms worsen
Diagnosis Not yet recruitingThis study tests a new eye scan that uses artificial intelligence to find changes linked to Alzheimer's disease. Researchers will compare the scan results with a blood test in 200 adults with mild memory problems. The goal is to see if this quick, non-invasive scan can help detec…
Matched conditions: COGNITIVE DYSFUNCTION
Sponsor: Eli Lilly and Company • Aim: Diagnosis
Last updated May 04, 2026 16:23 UTC
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Mindfulness app may ease burnout for Shift-Working nurses
Symptom relief Not yet recruitingThis study tests whether using a mobile app or virtual reality for short mindfulness and breathing sessions can lower stress, burnout, and improve sleep and thinking in nurses who work rotating shifts. About 300 nurses will practice 10 minutes a day, 5 times a week for 8 weeks. T…
Matched conditions: COGNITIVE DYSFUNCTION
Phase: NA • Sponsor: Chang Shih-Chin • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Could an old antibiotic shield the brain in sickle cell disease?
Symptom relief Not yet recruitingThis study tests whether minocycline, an antibiotic that reduces brain inflammation, can safely prevent or reverse memory and thinking problems in adults with sickle cell disease. About 30 participants will receive either a low dose, high dose, or placebo for one year. Researcher…
Matched conditions: COGNITIVE DYSFUNCTION
Phase: PHASE1 • Sponsor: University of Cincinnati • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Can brain games clear the fog? new study tests two training methods for Post-Viral cognitive struggles
Symptom relief Not yet recruitingThis study compares two brain training programs for adults with long-lasting brain fog after a viral infection, including from COVID-19 or ME/CFS. About 30 participants will do online games and a gentle nerve stimulation over 2-4 weeks, with follow-ups for 6 months. The goal is t…
Matched conditions: COGNITIVE DYSFUNCTION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 04, 2026 16:21 UTC
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Your eyes might predict dementia risk: new study investigates
Knowledge-focused Not yet recruitingThis study looks at whether tracking eye movements can help detect early cognitive problems in older adults. Researchers will use special glasses to measure how 210 people over age 65 move their eyes while doing simple tasks. The goal is to find a non-invasive way to screen for m…
Matched conditions: COGNITIVE DYSFUNCTION
Sponsor: National Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC