BENIGN PROSTATIC HYPERPLASIA

This study compares two ways of injecting BOTOX into the prostate for men with benign prostatic hyperplasia (BPH) who still have bothersome urinary symptoms despite medication. One group receives BOTOX only in the prostate gland, while the other gets injections in the prostate, b…

This study compares a new procedure called high-frequency irreversible electroporation (H-FIRE) to standard surgery (TURP) for treating benign prostatic hyperplasia (enlarged prostate). 118 men aged 40 and older with moderate to severe symptoms are participating. H-FIRE uses elec…

This study tested a closed-system bladder irrigation device designed to reduce urinary tract infections after endoscopic urologic surgery. 240 patients undergoing prostate or bladder tumor surgery were randomly assigned to use the new device or standard irrigation. The device all…

This completed study tested an artificial intelligence model called BEAM that combines MRI scans with a blood test (cell-free DNA) to improve prostate cancer diagnosis. Over 1,600 men participated, including those with healthy prostates, benign enlargement, or prostate cancer. Th…

This study compared two surgical techniques for treating benign prostatic hyperplasia (BPH): bipolar enucleation and thulium laser enucleation. Sixty men with large prostates (80 grams or more) were randomly assigned to one of the two procedures. Researchers measured operation ti…

This study tested whether a mobile app that teaches patients about prostate surgery can improve their experience. 68 patients were split into two groups: one used the app, the other received standard care. Researchers measured anxiety, fear, pain, and satisfaction before and afte…

This study tested a special type of prostate surgery designed to preserve ejaculation in men with an enlarged prostate. The surgery removes extra prostate tissue while protecting the area around the ejaculatory duct. Researchers followed 108 sexually active men for 3 months to se…

This study tested whether a nerve block (injecting numbing medicine near the tailbone) can reduce pain and the need for opioid painkillers after transurethral prostate resection (TURP) surgery. Sixty men undergoing TURP were split into two groups: one received the nerve block plu…

This study tested a drug called Tanzânia in 295 men who have both erectile dysfunction and an enlarged prostate (benign prostatic hyperplasia). The goal was to see if the drug improves erectile function better than a placebo. Participants took the drug or a dummy pill for a perio…

This study tested whether wearing a white noise sleep mask after prostate surgery (TUR-P) improves sleep quality and comfort. 70 adults who had elective surgery used the mask or standard care. The goal was to see if blocking hospital noise could help patients rest better and feel…

This study looked at 50 elderly men with an enlarged prostate who needed a urinary catheter. Doctors compared blocking blood flow to one side of the prostate versus both sides. The goal was to see if the simpler one-sided procedure could help patients stop using catheters just as…

This study tested a new device called Optilume BPH, which is a balloon coated with medicine that is inflated inside the prostate to open the urinary passage. The goal was to see if it safely improves moderate-to-severe urinary symptoms in men with an enlarged prostate. Eighty men…

This study tested whether listening to relaxing instrumental music during prostate surgery helps reduce anxiety and pain afterward. 135 men having a specific type of prostate surgery were randomly assigned to either listen to music or receive standard care. Researchers measured a…

This completed Phase I safety trial tested whether using the UroLift system—a device that lifts and holds enlarged prostate tissue out of the way—before stereotactic ablative body radiotherapy (SABR) is safe for men with both prostate cancer and benign prostatic hyperplasia (BPH)…

This study compared penile length in 200 adult men undergoing cystoscopy under spinal anesthesia versus general anesthesia. Researchers measured length and asked surgeons to rate satisfaction with access. The goal was to see if anesthesia choice affects penile size during the pro…

This study looked at 120 men who had HoLEP surgery for an enlarged prostate. Researchers wanted to see if bowel problems before surgery made recovery harder. Patients filled out questionnaires about bowel and urinary symptoms before and after surgery. The goal was to learn how bo…

This study looked at 132 men aged 55-80 who had surgery for an enlarged prostate. Researchers compared two common procedures—HoLEP and TURP—to see if one affects memory and thinking more than the other. Participants took thinking tests before surgery and three months after. The g…

This study looked at 130 men aged 50+ with enlarged prostate (BPH) causing urinary symptoms. Researchers used an ultrasound to measure how far the prostate bulges into the bladder, then tracked symptom changes over 6 months of standard medication. The goal was to see if this simp…

This completed registry study collected real-world data on 99 patients receiving HydroPearl microspheres to block blood flow to conditions like uterine fibroids, arteriovenous malformations, hypervascular tumors, and benign prostatic hyperplasia. The procedure was done through th…