Does anesthesia choice affect clotting in prostate surgery? a trial investigates

NCT ID NCT07734233

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial compares spinal anesthesia (using bupivacaine) with general anesthesia in men undergoing transurethral resection of the prostate (TURP) for benign prostatic hyperplasia. Researchers measure blood clotting and breakdown markers before surgery and at 1 and 24 hours after, to see if the type of anesthesia influences coagulation and fibrinolysis. The study also tracks blood pressure, heart rate, and complications during and after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Spinal anesthesia (bupivacaine) or general anesthesia (propofol, fentanyl, rocuronium, sevoflurane)
What this could lead to
If one anesthesia method proves safer for blood clotting, it could guide choices for prostate surgery patients.
What could go wrong
This is a small, early-stage study focused on lab tests, not clinical outcomes. Results may not change practice.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sultangazi Haseki Training and Research Hospital

    Istanbul, Istanbul, 34265, Turkey (Türkiye)

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