Could BOTOX shots in multiple prostate zones ease urinary symptoms?

NCT ID NCT07645456

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways of injecting BOTOX into the prostate for men with benign prostatic hyperplasia (BPH) who still have bothersome urinary symptoms despite medication. One group receives BOTOX only in the prostate gland, while the other gets injections in the prostate, bladder neck, and urethra. The goal is to see if the broader approach better improves urine flow and reduces symptoms over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Botulinum Toxin Type A (BOTOX)

What this could lead to

If successful, this combined injection approach could offer a less invasive, drug-free option for men with enlarged prostate who have not responded to standard medications.

What could go wrong

This is an early-phase study with only 60 participants, so results may not apply to all patients. BOTOX injections can cause temporary side effects like pain or urinary tract infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia Lower Urinary Tract Symptoms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Benha University Hospitals

    Banhā, Qalyubia Governorate, Egypt