Could BOTOX shots in multiple prostate zones ease urinary symptoms?

NCT ID NCT07645456

Completed Disease control Sponsor: Benha University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways of injecting BOTOX into the prostate for men with benign prostatic hyperplasia (BPH) who still have bothersome urinary symptoms despite medication. One group receives BOTOX only in the prostate gland, while the other gets injections in the prostate, bladder neck, and urethra. The goal is to see if the broader approach better improves urine flow and reduces symptoms over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Botulinum Toxin Type A (BOTOX)
What this could lead to: If successful, this combined injection approach could offer a less invasive, drug-free option for men with enlarged prostate who have not responded to standard medications.
What could go wrong: This is an early-phase study with only 60 participants, so results may not apply to all patients. BOTOX injections can cause temporary side effects like pain or urinary tract infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BENIGN PROSTATIC HYPERPLASIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia Lower Urinary Tract Symptoms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BENIGN PROSTATIC HYPERPLASIA

Contacts and locations

Locations

Benha University Hospitals

Banhā, Qalyubia Governorate, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.