New Needle-Free prostate treatment could replace surgery
NCT ID NCT05306145
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new procedure called high-frequency irreversible electroporation (H-FIRE) to standard surgery (TURP) for treating benign prostatic hyperplasia (enlarged prostate). 118 men aged 40 and older with moderate to severe symptoms are participating. H-FIRE uses electrical pulses to destroy excess prostate tissue without cutting, while TURP surgically removes tissue. The goal is to see if H-FIRE is as effective at improving urine flow and symptoms, with potentially fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High frequency irreversible electroporation (H-FIRE) procedure
What this could lead to
If H-FIRE works as well as TURP but with fewer side effects, it could offer men with enlarged prostate a less invasive treatment option.
What could go wrong
This is a small, single-center trial with 118 participants, so results may not apply to everyone. H-FIRE is still experimental and may not be as effective or safe as standard surgery.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Haifeng Wang
Shanghai, China