Smart AI could slash unnecessary prostate biopsies

NCT ID NCT06589154

Completed Diagnosis Sponsor: Shanghai Changzheng Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This completed study tested an artificial intelligence model called BEAM that combines MRI scans with a blood test (cell-free DNA) to improve prostate cancer diagnosis. Over 1,600 men participated, including those with healthy prostates, benign enlargement, or prostate cancer. The goal was to see if the AI could more accurately predict cancer than current PSA tests, potentially reducing the need for invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Multi-modal artificial intelligence model (BEAM) combining mpMRI and cfDNA analysis
What this could lead to: If successful, this AI tool could help doctors more accurately detect prostate cancer and avoid unnecessary biopsies, especially for men with borderline PSA levels.
What could go wrong: This is a completed study, but the AI model's real-world performance may vary. It was tested against biopsy results, and further validation is needed before routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BENIGN PROSTATIC HYPERPLASIA HEALTHY PEOPLE PROSTATE CANCER

Contacts and locations

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Locations

Cancer Hospital, Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, 100021, China
Changhai Hospital

Shanghai, Shanghai Municipality, 200433, China
Jiangsu Provincial People's Hospita

Nanjing, Jiangsu, 210029, China
Ningbo No. 1 Hospita

Ningbo, Zhejiang, 315010, China
Northern Jiangsu People's Hospita

Yangzhou, Jiangsu, 225001, China
Shanghai Changzheng Hospital

Shanghai, Shanghai Municipality, 201209, China
The First Affiliated Hospital of Soochow University

Suzhou, Jiangsu, 215006, China
The First Aﬃliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, 510120, China
West China Hospital, Sichuan University

Chengdu, Sichuan, 610041, China
Zhongda Hospital, Southeast University

Nanjing, Jiangsu, China

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