Shanghai Changzheng Hospital

This early-stage study is testing a single injection of stem cells (hiSCs) directly into the knee joint of people with rheumatoid arthritis (RA). The main goal is to see if the injection is safe and well-tolerated. Researchers will also check if it helps reduce knee pain, stiffne…

This early-stage study is testing whether the antibiotic rifaximin can safely reduce liver fat in people with metabolic-associated fatty liver disease (MAFLD). Up to 40 participants will take the drug daily for 24 weeks while maintaining their usual diet and exercise. The main go…

This study is testing a new drug called IBI311 against the standard steroid treatment for active, moderate-to-severe Thyroid Eye Disease (TAO). It will enroll 64 adults who have not yet received steroid treatment for their eye condition. The main goal is to see which treatment is…

This early-stage study is testing whether a gut-targeted antibiotic called rifaximin-α can reduce fat buildup in the liver for people with metabolic dysfunction-associated steatotic liver disease (MASLD). Sixty participants will be assigned to take the drug or not for 24 weeks wh…

This study is testing an investigational drug called IBI311 in people with inactive but moderate-to-severe Thyroid Eye Disease (TAO). The goal is to see if the drug can safely reduce eye bulging (proptosis) and improve double vision. Researchers will enroll about 50 participants …

This study is testing a combination of two existing drugs, anlotinib and sintilimab, as a first treatment for advanced colorectal cancer that has spread but not to the liver. The goal is to see if this 'chemotherapy-free' approach can control the cancer effectively with fewer sid…

This study is testing whether a new drug called Tetuzumab can help people with moderate to severe Thyroid Eye Disease who didn't get enough benefit from standard steroid treatments. Researchers will give the drug to 96 participants to see if it reduces eye bulging, inflammation, …

This study aims to track the long-term health of over 4,000 adults in Shanghai to understand how heart, kidney, and metabolic conditions like diabetes and high blood pressure develop and interact over time. It is a follow-up to health data collected from the same group of people …

This study aims to understand how giving pancreatic enzyme pills affects blood sugar levels and other hormones in people with chronic pancreatitis. It will observe 80 participants who have the condition but currently have normal blood sugar. The main goal is to see if this common…

This study aims to find out if the amount of iron in a person's tears is connected to how severe their dry eye disease is. Researchers will compare tear samples from people with dry eyes to samples from people with healthy eyes. They hope this research could lead to a new way to …

This study aims to understand how Thyroid-Associated Ophthalmopathy (TAO), which causes bulging eyes and limited eye movement, affects how people move their eyes and look at things. Researchers will use non-invasive eye-tracking technology to record the gaze patterns of 100 parti…