Could a gut antibiotic shrink fatty liver? small trial aims to find out
NCT ID NCT07185932
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage trial is testing whether the antibiotic rifaximin can reduce liver fat in people with metabolic fatty liver disease. About 40 adults will take rifaximin pills three times daily for up to 48 weeks, while maintaining diet and exercise. The main goal is to see if liver fat decreases on MRI scans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
rifaximin (Xifaxan)
What this could lead to
If it works, this could point toward a new treatment option for metabolic fatty liver disease using an existing antibiotic.
What could go wrong
This is a very early, small pilot study with only 40 people and no placebo group, so results may not be reliable or generalizable. Rifaximin can cause side effects like nausea or diarrhea.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Changzheng Hospital, Naval Medical University, shanghai, China
RECRUITINGShanghai, Shanghai Municipality, 200003, China
Contact Phone: •••-•••-•••• Email: •••••@•••••