Shanghai Changzheng Hospital

This study compares two surgical techniques for people with severe neck spinal cord compression caused by a hardened ligament. About 167 adults will be randomly assigned to receive either a newer front-of-neck procedure (ACAF) or a standard back-of-neck procedure (laminoplasty). …

This early-phase trial tests whether combining two antibodies (anti-IGF-1R and anti-PD-1) can safely control metastatic castration-resistant prostate cancer (mCRPC). Seven men with advanced disease that has stopped responding to standard hormone therapy will receive the combinati…

This early-phase trial tests a new type of immune cell therapy (PSMA-UCAR T cells) in 3 men with advanced prostate cancer that no longer responds to standard treatments. The main goal is to check safety and find the right dose, not to cure the disease. Participants must have meta…

This early-phase trial tests a new treatment for men with advanced prostate cancer that has stopped responding to standard therapies. The treatment uses the patient's own immune cells, which are modified in a lab to better recognize and attack cancer cells. Up to 18 participants …