Can a prostate implant ease urinary problems during cancer radiation?
NCT ID NCT05311527
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase I safety trial tested whether using the UroLift system—a device that lifts and holds enlarged prostate tissue out of the way—before stereotactic ablative body radiotherapy (SABR) is safe for men with both prostate cancer and benign prostatic hyperplasia (BPH). Fifteen men with low- to intermediate-risk prostate cancer and BPH received the UroLift implant followed by SABR. The main goal was to check for serious complications within 90 days after treatment, with secondary goals looking at urinary, sexual, and bowel quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- UroLift implant and stereotactic ablative body radiotherapy (SABR)
- What this could lead to
- If successful, this approach could offer a way to manage BPH symptoms during prostate cancer radiation, potentially improving urinary quality of life.
- What could go wrong
- This is a very small, early safety trial with only 15 participants, so results may not apply widely. The combination could still cause unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Texas Southwestern Medical Center - Dallas
Dallas, Texas, 75390, United States
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