BARIATRIC SURGERY

This study tests whether giving an intravenous iron supplement before weight-loss surgery can prevent anemia and improve quality of life in obese patients with low iron levels. About 200 participants will receive either the iron infusion or a placebo before their surgery. The goa…

This study tests whether taking tirzepatide for three months before bariatric surgery can reduce inflammation and lead to better weight loss and health improvements after surgery. About 50 adults with obesity and related health problems will either take the drug or not before the…

This study tests a new way to follow patients after weight-loss surgery. Instead of regular clinic visits, patients use a connected scale at home to track their weight. The care team then adjusts follow-up based on the results. The goal is to help more patients maintain healthy w…

This study tests a modified version of sleeve gastrectomy (a common weight-loss surgery) to see if it can reduce acid reflux, a frequent side effect. About 44 adults with obesity and GERD will be randomly assigned to the standard or modified surgery. The main goal is to measure c…

This study tests whether taking extra protein every day and doing supervised strength training once a week can help people who have had weight-loss surgery keep their muscle. About 400 adults scheduled for bariatric surgery will be randomly assigned to either standard care or sta…

This study looks at whether taking whey protein and collagen supplements, along with doing resistance exercises, can help people keep their muscle mass after bariatric surgery. About 35 adults who are having the surgery will be split into groups to compare different combinations …

This study tests a tailored version of SADI-S weight-loss surgery that adjusts the bypass length to each patient's anatomy. It aims to improve weight loss and reduce vitamin deficiencies. The study includes 40 adults with obesity, either as a first surgery or after a failed sleev…

This study compares two weight-loss surgeries for people with severe obesity and acid reflux (GERD). About 560 participants will be randomly assigned to either a newer procedure (Nissen-Sleeve) or the standard Roux-en-Y gastric bypass. The main goal is to see if the newer surgery…

This study looks at whether a supervised exercise program after bariatric surgery helps people keep muscle mass and bone density. About 54 adults who are waiting for weight-loss surgery will either exercise or not. The goal is to see if exercise can prevent muscle loss and keep b…

This early study tests a new, less invasive procedure that uses magnets to create a shortcut in the small intestine. The goal is to help control type 2 diabetes and manage weight in people who have already had weight-loss surgery or who have diabetes. Only 5 participants will be …

This study looks at the best amount of a green fluorescent dye (indocyanine green) to use during repeat weight loss surgery. The dye helps doctors see blood flow in real time. About 108 people with obesity will get different doses to find the smallest amount that works well. The …

This study tests whether adding a drug called Suzetrigine to standard pain management can lower the amount of opioids needed after weight-loss or heart surgery. About 235 adults aged 18-85 will take part. The goal is to reduce pain and opioid use, helping patients recover with fe…

This study tests whether a special ultrasound-guided nerve block (M-TAPA) can reduce pain and the need for strong painkillers after laparoscopic sleeve gastrectomy, a common weight-loss surgery. About 60 adults having this surgery will either receive the block or standard care. T…

This study tests whether a program of respiratory muscle training (breathing exercises) can improve heart, lung, and exercise capacity in people who recently had bariatric surgery for obesity. Researchers will enroll 52 adults aged 18 to 60 and measure changes in breathing streng…

This study tests whether lidocaine or dexmedetomidine works better for pain relief after laparoscopic sleeve gastrectomy (weight loss surgery). Forty adults aged 20-50 with a BMI of 35-50 will receive one of the two drugs during surgery. Researchers will measure pain levels, how …

This study tests whether a mild electrical nerve stimulator (TENS) placed on the skin can reduce breathing problems after bariatric surgery in people with severe obesity. About 70 participants will receive either TENS or a placebo patch. The main goal is to see if the diaphragm w…

This study looks at how the stomach and intestines digest food after bariatric surgery. Researchers will collect digestive samples and use a special capsule that measures things like acidity and movement inside the gut. The goal is to better understand digestion in people who hav…

This study looks at how gut bacteria influence blood sugar changes after bariatric (weight-loss) surgery. Researchers will measure blood sugar and analyze stool samples from 120 adults before and after surgery. The goal is to understand the role of gut microbes, not to test a new…

This study looks at 200 adults who need a second weight-loss surgery (revision bariatric surgery) to see if using a robot or standard laparoscopic tools leads to fewer complications. The main goal is to compare rates of problems like leaks, bleeding, and infections between the tw…

This study is for teens and young adults aged 12 to 24 who are planning to have weight loss surgery (sleeve gastrectomy). Researchers want to understand how the body changes after surgery and why some people lose more weight than others. They will also test if adding a medication…

This study looks at whether a special diet that promotes a healthy mix of gut bacteria can improve weight loss and eating habits after bariatric surgery. About 60 adults who are having weight-loss surgery will be split into two groups: one gets standard nutrition advice, the othe…

This study compares two ways of using a breathing machine during weight-loss surgery in 40 adults with obesity. The goal is to see which method keeps oxygen levels higher and puts less pressure on the lungs. Results may help doctors choose safer breathing settings for future surg…

This study looks at how body weight and bariatric surgery change natural chemicals in scalp hair. Researchers will also measure hair thinning and muscle loss in the first 6 months after surgery. The study includes 60 adults: some with severe obesity scheduled for surgery, and som…

This study follows 2000 adults who are having weight-loss surgery to understand how pain and daily activities change afterward. Researchers will ask patients about their pain, side effects, and ability to do everyday tasks. The goal is to learn what influences pain after surgery,…

This study aims to find out why some people lose more weight than others after obesity treatments like surgery or medication. Researchers will look at eating behaviors, thinking patterns, and biological markers in 100 adults with obesity. The goal is to better personalize care an…

This observational study looks at the bacteria in dental plaque of 170 people with obesity (BMI 30+) who are scheduled for bariatric surgery. Researchers want to see if the types and amounts of mouth bacteria differ between those with obesity (BMI 30-35) and those with morbid obe…