New surgery may offer better reflux control for obese patients

NCT ID NCT07158008

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two surgical options for people with severe obesity and acid reflux (GERD). Half of the 560 participants will get a newer procedure called Nissen-Sleeve Gastrectomy, which combines stomach reduction with a reflux barrier; the other half will get the standard Roux-en-Y Gastric Bypass. The main goal is to see if the newer surgery controls reflux just as well one year after the operation, while also tracking weight loss and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nissen-Sleeve Gastrectomy (N-SG) and Roux-en-Y Gastric Bypass (RYGB) surgical procedures

What this could lead to

If successful, this could show that Nissen-Sleeve Gastrectomy is as good as or better than the standard bypass for controlling acid reflux while offering simpler long-term care.

What could go wrong

This is a single-center trial with one-year follow-up, so results may not apply broadly. Both surgeries carry risks like infection, nutritional issues, and complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Szpital Uniwersytecki w Krakowie

    RECRUITING

    Krakow, 30-688, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••