New surgery may offer better reflux control for obese patients

NCT ID NCT07158008

Recruiting now Disease control Sponsor: Jagiellonian University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two surgical options for people with severe obesity and acid reflux (GERD). Half of the 560 participants will get a newer procedure called Nissen-Sleeve Gastrectomy, which combines stomach reduction with a reflux barrier; the other half will get the standard Roux-en-Y Gastric Bypass. The main goal is to see if the newer surgery controls reflux just as well one year after the operation, while also tracking weight loss and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nissen-Sleeve Gastrectomy (N-SG) and Roux-en-Y Gastric Bypass (RYGB) surgical procedures
What this could lead to: If successful, this could show that Nissen-Sleeve Gastrectomy is as good as or better than the standard bypass for controlling acid reflux while offering simpler long-term care.
What could go wrong: This is a single-center trial with one-year follow-up, so results may not apply broadly. Both surgeries carry risks like infection, nutritional issues, and complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease morbid obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BARIATRIC SURGERY GASTRO ESOPHAGEAL REFLUX SEVERE OBESITY

Contacts and locations

Locations

Szpital Uniwersytecki w Krakowie
RECRUITING

Krakow, 30-688, Poland

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