ACUTE RESPIRATORY FAILURE

This study tested whether a special breathing mask (non-invasive ventilation) could help patients who develop serious breathing problems after abdominal surgery. It compared the mask to standard oxygen therapy to see if it could prevent the need for a breathing tube and ventilato…

This study tested whether a phone-based support and rehab program could improve quality of life for adults recovering from severe breathing failure that required a ventilator. Nearly 2,000 participants were involved. The program provided guidance on recovery in the ICU, hospital …

This study tested two ways to give oxygen to adults hospitalized with sudden, severe breathing failure. Researchers compared standard oxygen therapy to a newer method called high-flow nasal oxygen to see which one led to better survival rates after 28 days. The goal was to find t…

This large trial aimed to find out which of two common sedative medications is safer when doctors place a breathing tube in critically ill adults. Researchers compared ketamine and etomidate in over 2,300 patients to see which drug led to fewer dangerous drops in blood pressure a…

This study tested two different settings on non-invasive breathing machines for patients hospitalized with acute, severe breathing failure. It focused on patients with obesity (BMI ≥ 30) who are at risk for sleep apnea or poor breathing while asleep. Researchers compared a standa…

This pilot study tested three different strategies for managing sedation and pain in ICU patients who need help breathing from a machine. The main goal was to see if a new 'pain-first' approach using fentanyl was practical to use. Researchers also looked at how these strategies a…

This study aimed to find out which of two common sedative drugs is safer when doctors need to quickly place a breathing tube in critically ill patients. Researchers compared ketamine and propofol in 207 patients to see which one caused fewer dangerous drops in blood pressure duri…

This study tested a new, non-invasive imaging method called Electrical Impedance Tomography (EIT) to see if it could better predict when patients in intensive care are ready to breathe on their own after being on a ventilator. Researchers compared this new method against standard…

This study tested a new online tool called TRACH-Support, designed to help families and medical teams make difficult decisions about long-term breathing support for patients who cannot breathe on their own. Over 100 family members and healthcare providers reviewed the tool and sh…

This study aimed to understand how common and serious high carbon dioxide levels are in patients admitted to intensive care units (ICUs). Researchers observed 862 adult ICU patients who had this breathing problem to learn what factors lead to it and how it affects patient recover…

This study looked back at the records of 1,248 adult patients in an intensive care unit (ICU) to see if the type of illness they had when admitted (like sepsis or respiratory failure) was linked to their chance of dying in the ICU. Researchers wanted to know if these diagnoses pr…

This study observed 55 adults hospitalized with sudden, severe breathing failure. Researchers measured patients' breathlessness, how well different parts of their lungs were working, and the strength of their main breathing muscle (the diaphragm) over time. The goal was to learn …

This study aimed to compare three different methods for assessing the risk of 'self-induced lung injury' in hospitalized patients with severe breathing problems who are using a common type of breathing machine (pressure-support ventilation). Researchers enrolled 16 adult patients…