ACUTE RESPIRATORY FAILURE

This study looked at whether specialized physiotherapy, which combines breathing treatments and early movement, could lower the chance of serious breathing problems in the week after a breathing tube is removed. It involved 245 ICU patients at high risk for breathing failure. The…

This study tested whether giving oxygen through a high-flow nasal cannula helps more people survive severe breathing failure compared to standard oxygen. Over 1,500 adults with low blood oxygen levels were randomly assigned to one of the two oxygen methods. The main goal was to s…

This study looked at over 2,300 critically ill adults who needed an emergency breathing tube. It compared two common sedatives, ketamine and etomidate, to see which one leads to fewer deaths and heart problems. The goal was to find the safer option for this high-risk procedure.

This study looked at whether using a noninvasive breathing mask (NIV) could help patients who develop breathing problems after abdominal surgery avoid needing a breathing tube. 300 adults who had abdominal surgery and then had trouble breathing were randomly assigned to receive e…

This study followed over 4,000 patients in Chinese ICUs who needed breathing support for acute respiratory failure. Researchers collected data on treatments, outcomes, and costs to better understand the disease burden. The goal is to improve care and inform future guidelines.

This study looked at 55 adults with severe breathing problems to understand how their lungs and diaphragm work. Researchers measured breathing difficulty, lung ventilation, and diaphragm function to find out who might need a breathing tube. The goal was to learn more about the co…

This study examined how often patients in the intensive care unit (ICU) have high carbon dioxide levels (hypercapnia) along with breathing failure. Researchers tracked 862 adults to understand what causes this condition and how it affects patient outcomes. The goal was to gather …

This study reviewed records of 1248 adults admitted to an intensive care unit (ICU) in 2025. Researchers wanted to see if the reason for admission (like sepsis or breathing failure) could predict who dies in the ICU, beyond what standard severity scores show. The goal is to impro…

This study tested a new way to predict if patients on breathing machines can safely have the tube removed. Researchers used a special imaging technique called electrical impedance tomography (EIT) to measure how well the lungs fill with air during a breathing trial. The goal was …

This study tested a personalized online tool called TRACH-Support that helps families and medical teams decide whether to use a tracheostomy (a tube in the throat) for patients who need long-term breathing help. 105 family members and healthcare providers used the tool and gave f…

This pilot study looked at three different ways to manage pain and sedation in adults on breathing machines in the ICU. The goal was to see if these approaches were practical and could help reduce time on the ventilator. The study included 90 participants and focused on how well …

This study compared two common sedatives, propofol and ketamine, used when placing a breathing tube in critically ill patients. The goal was to see which drug better maintains stable blood pressure and reduces complications. Over 200 adults with acute respiratory failure took par…

This study looked at 16 adults on breathing machines (ventilators) to see if simpler tests could spot lung injury risk as well as the standard method. Researchers compared three different measurement techniques. The goal was to find safer ways to monitor patients with acute respi…

This study involved 500 ICU patients on ventilators to see if the timing of pressure measurements changes how doctors estimate lung injury risk. Researchers compared pressures taken at different moments during a breath-hold to see which best predicts complications. The goal is to…

This study tested a telemedicine program to help adults who needed a breathing machine for acute respiratory failure. The program included support in the ICU, regular hospital ward, and after discharge. Researchers measured quality of life 90 days later in 1,916 participants. The…

This study looked at over 2,400 critically ill patients who needed breathing machines and medications for shock. Researchers compared early feeding through a tube into the stomach (enteral nutrition) versus feeding through a vein (parenteral nutrition) to see which approach reduc…