ACUTE RESPIRATORY FAILURE

This study tests whether giving steroids based on a patient's immune status can reduce deaths in severe pneumonia with respiratory failure. About 500 ICU patients will receive methylprednisolone, with doses adjusted according to their inflammatory profile. The goal is to find out…

This study tests two methods to train the breathing muscles of patients with respiratory failure who are on mechanical ventilators. One method slowly increases the effort needed to trigger a breath, while the other gradually reduces the machine's support. The goal is to see which…

This pilot study tests whether a simple tip sheet can help ICU doctors have better conversations with families of patients on breathing machines, especially families from different racial backgrounds. About 106 doctors and their patients' families will take part. The goal is to s…

This small pilot study will test two common blood pressure medicines—nicardipine and sodium nitroprusside—in 12 patients with acute respiratory failure and high blood pressure. Researchers will use a special imaging technique called electrical impedance tomography to see how thes…

This study looks at whether a simple, non-invasive ultrasound of the diaphragm can help predict which older adults (75+) with sudden shortness of breath will develop severe breathing failure. Researchers will measure diaphragm movement and thickness in 145 emergency patients and …

This study will collect information from 1,200 patients in the French West Indies and Guiana who received ECMO, a machine that helps the heart and lungs. Researchers aim to track survival rates and complications to better understand how ECMO works in this region. The study does n…

This study looks at whether a chest CT scan gives important new information beyond a simple chest X-ray for ICU patients with respiratory failure. Researchers will review records of 50 patients to see if CT findings changed their treatment. The goal is to find out if some CT scan…