ACUTE RESPIRATORY FAILURE

This study tests a new AI device called EMILY that automatically gives the right amount of oxygen to patients with breathing failure and alerts doctors if their condition worsens. Researchers will enroll 20 adults in the hospital to see how well the device keeps oxygen levels in …

This study is testing a new device called the MiniLung petite kit in 20 newborns and children weighing 2 to 8 kilograms who have severe breathing or heart failure. The device is used with a machine that takes over the work of the lungs and heart (ECMO). The goal is to see if it s…

This study compares two methods (waveform capnography and colorimetric carbon dioxide detection) to confirm that a breathing tube is correctly placed in the windpipe of critically ill adults. About 1,332 patients in emergency rooms or intensive care units will be enrolled. The go…

This study looks at whether a quick ultrasound of a large vein (the inferior vena cava) can help emergency doctors figure out why a patient is having sudden trouble breathing. The goal is to tell apart fluid in the lungs from heart problems versus other causes. Researchers will e…

This study explores whether virtual reality (VR) can help patients in the Intensive Care Unit (ICU) feel more relaxed, improve their mood, and keep their minds active. About 32 adults with serious breathing problems or sepsis will use VR for 15-45 minutes each day for up to 5 day…

This study looks at how the type of oxygen monitor and the target oxygen level affect the amount of oxygen given to ICU patients on high-flow nasal oxygen therapy. Researchers will test two different oximeters and two oxygen targets in 30 adults to see which combination leads to …

This study observes 325 adults hospitalized with acute respiratory failure who are receiving non-invasive breathing support like high-flow oxygen or a mask ventilator. Researchers will track which patients eventually need a breathing tube and why. The goal is to find early warnin…

This study uses a non-invasive chest monitor (EIT) to see how air moves through the lungs of children with acute respiratory failure in the pediatric ICU. Researchers will observe how changes in ventilator settings, body position, and other treatments affect ventilation. The goal…

This study collects small breath and blood samples from 200 intensive care patients who are on breathing machines. Researchers will analyze proteins in the breath and compare them with DNA, RNA, and other markers in the blood. The goal is to find patterns that could help doctors …

This study is collecting information from 250 adults to develop an artificial intelligence model that can identify different types of acute respiratory failure. The goal is to help doctors personalize treatments for this serious breathing condition. Participants include those in …

This study compares two types of video laryngoscope blades (curved Macintosh vs. hyperangulated) to see which helps doctors successfully place a breathing tube on the first try in ICU patients with breathing failure. About 1,036 adults in the ICU who need a breathing tube will be…

This study is testing whether a common substance, sodium bicarbonate (baking soda), can be used as a safe contrast agent to create images of lung blood flow using a bedside device called electrical impedance tomography (EIT). The study involves 41 adults in the intensive care uni…

This study looks at how the brain and lungs work together in adults with severe breathing problems who need high-flow oxygen in the intensive care unit. Researchers will use special brain wave and oxygen level monitors to see if changes in brain activity can predict who will need…

This study aims to understand how adults who survive acute respiratory failure (ARF) and their family caregivers think about the first 6 months of recovery. Researchers want to see if expectations about recovery are linked to anxiety, depression, and stress in both survivors and …