Breath sniffing test could spot lung trouble in ventilator patients

NCT ID NCT06189924

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new way to check the health of ICU patients who are on breathing machines. Researchers collect a small sample of the air patients breathe out and analyze its proteins. They also take a blood sample to look for related changes in DNA, RNA, and other molecules. The goal is to find patterns that signal early signs of lung problems, so doctors can act faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple, non-invasive breath test that helps doctors detect lung complications earlier in critically ill patients.
What could go wrong
This is an early observational study, not a treatment trial. The patterns found may not be specific enough to reliably diagnose conditions in real time.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure Critical Illness Lung Injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institute of Molecular and Translational Medicine, Palacky University

    RECRUITING

    Olomouc, 77900, Czechia

  • University Hospital Olomouc

    RECRUITING

    Olomouc, 77900, Czechia

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