Can combining two oxygen devices help patients breathe better?
NCT ID NCT07521254
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways of giving breathing support to adults with acute respiratory failure in the ICU. One group gets standard noninvasive ventilation (a mask that helps breathing), while two other groups get that plus a high-flow nasal cannula (a device that delivers warm, moist oxygen through the nose) at different times. The goal is to see if the combination improves oxygen levels and comfort more than the mask alone. The trial will include 75 patients and track results over 24 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-flow nasal cannula (HFNC) device and noninvasive ventilation (NIV) device
What this could lead to
If successful, this could show that combining two breathing support methods helps patients with acute respiratory failure breathe easier and need less time on a ventilator.
What could go wrong
This is a small, early-stage study with only 75 participants, so results may not apply to all patients. The devices are already in use, so no major new risks are expected, but individual responses vary.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Minya university hospitals
RECRUITINGMinya, Minya Governorate, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••