Which CO2 test is best for emergency breathing tube checks?

NCT ID NCT06934876

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two methods—waveform capnography and a color-changing carbon dioxide detector—to see which more accurately confirms that a breathing tube is in the right place (the windpipe) in critically ill adults. About 2,000 patients in emergency departments or intensive care units will be enrolled. The goal is to find out which test is more sensitive and specific, helping doctors make safer decisions during intubation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If this study succeeds, it could help doctors know which carbon dioxide test is more reliable for confirming breathing tube placement in emergency situations.

What could go wrong

This is an observational study comparing two existing tests, not testing a new treatment. Results may not apply to all patients or settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albany Medical Center

    RECRUITING

    Albany, New York, 12208, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University School of Medicine

    NOT_YET_RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hennepin Healthcare

    RECRUITING

    Minneapolis, Minnesota, 55415, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lahey Hospital & Medical Center

    RECRUITING

    Burlington, Massachusetts, 01805, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Sciences University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Regions Hospital

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rush University Medical Center

    NOT_YET_RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ohio State University College of Medicine

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wake Forest School of Medicine

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••