Which CO2 test is best for emergency breathing tube checks?

NCT ID NCT06934876

Recruiting now Knowledge-focused Sponsor: Brian Driver Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two methods—waveform capnography and a color-changing carbon dioxide detector—to see which more accurately confirms that a breathing tube is in the right place (the windpipe) in critically ill adults. About 2,000 patients in emergency departments or intensive care units will be enrolled. The goal is to find out which test is more sensitive and specific, helping doctors make safer decisions during intubation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If this study succeeds, it could help doctors know which carbon dioxide test is more reliable for confirming breathing tube placement in emergency situations.
What could go wrong: This is an observational study comparing two existing tests, not testing a new treatment. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY FAILURE

Contacts and locations

Locations

Albany Medical Center
RECRUITING

Albany, New York, 12208, United States
Duke University School of Medicine
NOT_YET_RECRUITING

Durham, North Carolina, 27710, United States
Hennepin Healthcare
RECRUITING

Minneapolis, Minnesota, 55415, United States
Lahey Hospital & Medical Center
RECRUITING

Burlington, Massachusetts, 01805, United States
Oregon Health and Sciences University
RECRUITING

Portland, Oregon, 97239, United States
Regions Hospital
RECRUITING

Saint Paul, Minnesota, 55101, United States
Rush University Medical Center
NOT_YET_RECRUITING

Chicago, Illinois, 60612, United States
The Ohio State University College of Medicine
RECRUITING

Columbus, Ohio, 43210, United States
Wake Forest School of Medicine
RECRUITING

Winston-Salem, North Carolina, 27157, United States

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