Ultrasound may reveal hidden causes of ventilator weaning failure

NCT ID NCT02723565

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study explores whether ultrasound can identify the reasons some patients fail to come off a mechanical ventilator. Researchers will scan the heart, lungs, and diaphragm of adults who have been on a ventilator for at least 24 hours and have not passed a spontaneous breathing trial. The goal is to see if ultrasound can accurately diagnose the physiological problem behind weaning failure, which could help doctors choose better treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If ultrasound can pinpoint the cause of weaning failure, doctors could tailor treatments to help more patients breathe on their own sooner.
What could go wrong
This is a very small, early study with only 7 participants, so results may not apply to all patients. Ultrasound may not be accurate enough to replace standard methods.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mount Sinai Hospital

    Toronto, Ontario, M5G 1X5, Canada

  • St. Michael's Hospital

    Toronto, Ontario, M5B 1W8, Canada

  • University Health Network

    Toronto, Ontario, M5G 2N2, Canada

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