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ICU intubation showdown: hyperangulated vs. macintosh blades

NCT ID NCT06322719

Knowledge-focused Sponsor: Hospital Clinico Universitario de Santiago Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two types of video laryngoscope blades—hyperangulated and Macintosh—to see which leads to successful intubation on the first try in ICU patients. Over 1,000 adults needing a breathing tube will be randomly assigned to one blade type. The goal is to find out if one blade reduces complications and improves success rates.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If one blade proves better, it could guide doctors to use the most effective tool for ICU intubations, potentially reducing complications.
What could go wrong
This is a device comparison study, not a new treatment. Results may show no clear winner, and findings may not apply outside ICUs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,036 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older. * Admitted to an Intensive Care Unit. * Need for tracheal intubation during the stay in the ICU. * The device to be used for intubation is a videolaryngoscope Exclusion Criteria: * Pregnancy or lactation. * Emergent tracheal intubation that does not allow for the randomization of the procedure. * Need for tracheal intubation with a device other than the videolaryngoscope (fiberoptic bronchoscope, direct laryngoscopy, tracheostomy, etc.). * Tracheal intubation performed outside the ICU (Emergency Department, Hospital ward, etc.).

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Conditions

The condition(s) this trial relates to.

acute respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute respiratory failure Intubation Intubation complication Intubation; difficult or failed Videolaryngoscopy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    29 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clínica Universidad de Navarra, Pamplona

    NOT_YET_RECRUITING

    Pamplona, Spain

  • Complejo Asistencial Universitario de León

    NOT_YET_RECRUITING

    León, Spain

  • Complejo Asistencial de Segovia

    NOT_YET_RECRUITING

    Segovia, Spain

  • Complexo Hospitalario Universitario de A Coruña

    RECRUITING

    A Coruña, Spain

  • Complexo Hospitalario Universitario de Ourense

    NOT_YET_RECRUITING

    Ourense, Spain

  • Complexo Hospitalario Universitario de Pontevedra

    NOT_YET_RECRUITING

    Pontevedra, Spain

  • Complexo Hospitalario Universitario Álvaro Cunqueiro de Vigo

    NOT_YET_RECRUITING

    Vigo, Spain

  • Hospital Clínico Universitario de Valencia

    NOT_YET_RECRUITING

    Valencia, Spain

  • Hospital General Universitario de Eche

    NOT_YET_RECRUITING

    Elche, Spain

  • Hospital General de Albacete

    NOT_YET_RECRUITING

    Albacete, Spain

  • Hospital Gregorio Marañón, Madrid

    NOT_YET_RECRUITING

    Madrid, Spain

  • Hospital Ribera Povisa Vigo

    RECRUITING

    Vigo, Spain

  • Hospital Universitario 12 de Octubre, Madrid

    NOT_YET_RECRUITING

    Madrid, Spain

  • Hospital Universitario Central de Asturias (HUCA), Oviedo

    NOT_YET_RECRUITING

    Oviedo, Spain

  • Hospital Universitario Donostia, San Sebastián

    RECRUITING

    San Sebastián, Spain

  • Hospital Universitario La Fe de Valencia

    NOT_YET_RECRUITING

    Valencia, Spain

  • Hospital Universitario La Paz, Madrid

    RECRUITING

    Madrid, Spain

  • Hospital Universitario La Princesa

    NOT_YET_RECRUITING

    Madrid, Spain

  • Hospital Universitario Lucus Augusti, Lugo

    RECRUITING

    Lugo, Spain

  • Hospital Universitario Marqués de Valdecilla, Santander

    NOT_YET_RECRUITING

    Santander, Spain

  • Hospital Universitario Puerta de Hierro, Majadahonda

    NOT_YET_RECRUITING

    Majadahonda, Spain

  • Hospital Universitario de Cabueñes, Gijón

    NOT_YET_RECRUITING

    Gijón, Spain

  • Hospital Universitario de Cáceres

    NOT_YET_RECRUITING

    Cáceres, Spain

  • Hospital Universitario de Gran Canaria Doctor Negrín

    NOT_YET_RECRUITING

    Las Palmas de Gran Canaria, Spain

  • Hospital Universitario de Móstoles

    NOT_YET_RECRUITING

    Móstoles, Spain

  • Hospital Virgen de las Nieves, Granada

    NOT_YET_RECRUITING

    Granada, Spain

  • Hospital de Denia

    NOT_YET_RECRUITING

    Denia, Spain

  • Hospital de la Santa Creu i Sant Pau, Barcelona

    NOT_YET_RECRUITING

    Barcelona, Spain

  • University Clinical Hospital of Santiago de Compostela

    RECRUITING

    Santiago de Compostela, A Coruña, 15866, Spain

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