Could a simple oxygen change help ICU patients breathe easier after tube removal?
NCT ID NCT05904652
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving high-flow oxygen through the nose just before removing a breathing tube is safe and acceptable for patients in intensive care with severe breathing problems. Only 2 patients took part, and the main goal was to see if a larger study is possible. The researchers compared this new approach to standard low-flow oxygen given after tube removal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High flow nasal oxygen delivery device
What this could lead to
If successful, this could lead to a larger trial testing whether high-flow oxygen before tube removal reduces the need for re-intubation.
What could go wrong
This is a very small feasibility study with only 2 participants, so results are not generalizable. It is designed to test recruitment and safety, not effectiveness.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Critical Care Medicine, Queen Elizabeth University Hospital
Glasgow, Scotland, G51 4TF, United Kingdom