New therapy aims to help ICU survivors recover mind and body

NCT ID NCT03431493

Completed Symptom relief Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether a therapy that combines behavioral activation for depression with physical rehabilitation is feasible for survivors of acute respiratory failure. Fifty-two adults who had been on life support in the ICU received home visits and phone calls from therapists over several weeks. The goal was to see if this approach could be delivered successfully and might improve both mental and physical recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Behavioral activation and rehabilitation therapy delivered via telephone and home visits
What this could lead to: If successful, this approach could provide a practical way to help ICU survivors recover both mentally and physically after a serious illness.
What could go wrong: This is a small pilot study focused on feasibility, not effectiveness. The intervention may not show clear benefits in larger trials.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure Depression depressive disorder respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL CARE DEPRESSION REHABILITATION RESPIRATORY INSUFFICIENCY

Contacts and locations

Locations

Johns Hopkins University

Baltimore, Maryland, 21205, United States

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