Spondylolisthesis
MONDO:0008475A condition in which there is forward displacement of a vertebral bone over the on below it.
Also known as: spondylolisthesis, spondylolisthesis (disease)
105 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Back surgery showdown: which fusion technique works best?
Disease control CompletedThis study looked at 60 adults with degenerative spondylolisthesis, a condition where a spine bone slips forward causing pain. All patients needed spinal fusion surgery. The researchers compared two surgical methods: one that fuses the back of the spine only, and another that als…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Spinal implants pass 24-Month safety check in 77 patients
Disease control CompletedThis study followed 77 adults who received spinal implants (PASS LP, PASS DEGEN, or PASS TULIP PRIME) to treat degenerative spine conditions like disc degeneration or spinal deformity. The main goal was to see if the bones fused properly after 24 months. Researchers also tracked …
Sponsor: Medicrea International • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Double fusion surgery shows promise for slipped vertebrae
Disease control CompletedThis study looked at 87 adults who had a two-step spinal fusion surgery for isthmic spondylolisthesis, a condition where a vertebra slips forward. The surgery combines an anterior approach (through the abdomen) with a posterior approach (through the back) to stabilize the spine. …
Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New spinal implant shows promise for chronic back pain
Disease control CompletedThis study tested a special spinal implant (the Keos Lumbar Interbody Fusion Device) in 25 adults with degenerative disc disease or related spine conditions. The goal was to see how well the device helped bones fuse and how it affected pain and quality of life. Participants had s…
Phase: NA • Sponsor: Invibio Ltd • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New back surgery study shows promise for disc disease patients
Disease control CompletedThis study followed 361 adults with degenerative disc disease who had minimally invasive spinal fusion surgery. The goal was to see how well these procedures reduce disability and pain over 5 years. Researchers compared different surgical approaches to find which works best for p…
Sponsor: Medtronic Spinal and Biologics • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New spine implants tested for safety in patients with back problems
Disease control CompletedThis study looked at the safety and performance of two types of expandable spine implants (MLX and XLX ACR) in 109 adults with degenerative disc disease, spondylolisthesis, or scoliosis. Researchers tracked complications, bone fusion, and improvement in nerve symptoms after surge…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New spine plate shows promise in fusion surgery study
Disease control CompletedThis study tested a new plate system used during spine fusion surgery in 75 adults with conditions like degenerative disc disease or scoliosis. The goal was to see if the plate is safe and helps bones fuse together properly. Researchers measured pain relief and fusion success ove…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New spinal implant shows promise in back surgery study
Disease control CompletedThis study looked at how safe and well a new spinal implant (Modulus ALIF System) works in 123 adults having back surgery. The patients had conditions like worn-out discs or slipped vertebrae. The main goals were to check for complications and see if the bones fused properly afte…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New 3D-Printed spine implant shows promise in small study
Disease control CompletedThis study tested a new 3D-printed titanium implant for spine fusion surgery in 36 adults with degenerative disc disease, spondylolisthesis, or scoliosis. The implant is designed to help bones in the spine grow together after surgery. Researchers looked at safety, how well the bo…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New scale could help predict fall risk for hospital patients in turkey
Diagnosis CompletedThis study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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Can a single day of therapy stop chronic pain after back surgery?
Prevention CompletedThis pilot study tested whether a one-day Acceptance and Commitment Therapy (ACT) workshop, plus a follow-up phone call, could help prevent chronic pain after back surgery. 45 adults scheduled for spinal surgery took part. The study focused on whether the workshop was acceptable …
Phase: NA • Sponsor: Samantha Meints • Aim: Prevention
Last updated Jun 27, 2026 12:28 UTC
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Which rehab works best after back surgery? new study aims to find out
Symptom relief CompletedThis study looked at different rehabilitation programs for 90 adults who had back surgery for degenerative lumbar disease. The goal was to see which rehab approach best reduces nerve pain, helps patients regain function, and improves quality of life. Participants were randomly as…
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Nerve block may cut opioid use in back surgery
Symptom relief CompletedThis study looked at whether adding a nerve block (called ESP block) to general anesthesia helps people undergoing lower back surgery. 50 adults were split into two groups: one got the nerve block plus anesthesia, the other got anesthesia alone. The goal was to see if the nerve b…
Phase: NA • Sponsor: Bangladesh Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Less invasive back surgery may offer faster relief for spinal stenosis patients
Symptom relief CompletedThis study compared two surgical approaches for people with a single level of lumbar spinal stenosis (a narrowed spine canal causing leg pain and trouble walking). 96 adults aged 40-75 were randomly assigned to receive either minimally invasive decompression and fusion or traditi…
Phase: NA • Sponsor: N.N. Priorov National Medical Research Center of Traumatology and Orthopedics • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Rehab showdown: which therapy eases back pain from slipped vertebrae?
Symptom relief CompletedThis completed study tested two 4-week rehabilitation programs in 58 adults aged 60-75 with mild spondylolisthesis (a slipped vertebra). One group did exercises plus physical therapy; the other did exercises plus myofascial trigger point therapy. Researchers measured pain, disabi…
Phase: NA • Sponsor: Józef Piłsudski University of Physical Education • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Less invasive back surgery may be just as good as major fusion
Symptom relief CompletedThis study looked at two types of surgery for people over 50 with a slipped vertebra (spondylolisthesis) and a narrowed spine canal (stenosis). One group had a smaller surgery to take pressure off the nerves (decompression alone), while the other had that plus a fusion with metal…
Sponsor: Kafrelsheikh University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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App-based therapy shows promise in preventing chronic pain after teen spinal surgery
Symptom relief CompletedThis study tested a mobile app called SurgeryPal that teaches teens coping skills before and after major spine surgery. 433 teens aged 12-18 were randomly assigned to use the app or receive standard education. The goal was to see if the app could reduce pain and prevent pain from…
Phase: NA • Sponsor: Seattle Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Physiotherapy students test muscle relief techniques on themselves
Symptom relief CompletedThis study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…
Phase: NA • Sponsor: Charles University, Czech Republic • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Where you inject matters: study tests best spot for back pain block
Symptom relief CompletedThis completed study looked at 90 people with lower back pain from conditions like herniated discs or spinal stenosis. Researchers compared two different target areas for injecting numbing medicine during a lumbar spine block to see which provides better pain relief and blood flo…
Phase: NA • Sponsor: Keimyung University Dongsan Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Spine surgery showdown: which approach helps patients recover faster?
Symptom relief CompletedThis study compared two types of spine surgery (XLIF and TLIF) in 55 adults with a slipped vertebra causing pain and leg symptoms. The goal was to see which procedure led to better function and less pain over two years. Results could help doctors choose the best surgical approach…
Sponsor: NuVasive • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Back brace after spine surgery: help or hype?
Symptom relief CompletedThis study looked at whether wearing a back brace after spinal fusion surgery improves pain and quality of life. 43 adults with degenerative spine conditions were randomly assigned to wear a brace or not. Researchers measured disability, pain, and general health at 6 weeks and 3 …
Phase: NA • Sponsor: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Who should control your sedation during surgery? new study compares options
Symptom relief CompletedThis study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New study pits two pain blocks against each other for spine surgery relief
Symptom relief CompletedThis study compared two ultrasound-guided pain blocks—caudal block and quadratus lumborum plane block—in 111 adults undergoing lumbar spine surgery. The goal was to see which provides better pain relief and reduces the need for opioid painkillers. Researchers measured how long it…
Phase: NA • Sponsor: Fayoum University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New turkish health survey could improve care for muscle and joint problems
Knowledge-focused CompletedThis study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…
Sponsor: Istanbul Bilgi University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Back surgery showdown: which procedure is better for spinal stenosis?
Knowledge-focused CompletedThis pilot study tested whether a larger trial is possible comparing two standard surgeries for lumbar spinal stenosis with a related condition called spondylolisthesis. The two procedures are decompression alone and decompression with fusion. The study enrolled 70 surgical candi…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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25-Year back surgery study: when is less really more?
Knowledge-focused CompletedThis study looked back at 25 years of medical records from 246 patients aged 50+ with lumbar spinal stenosis (a narrowing in the spine that can cause leg pain and trouble walking). Researchers compared patients who had a less invasive surgery (tubular decompression, with or witho…
Sponsor: University of Valencia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Physios take on ER duty: study tests if they can replace doctors for back pain
Knowledge-focused CompletedThis study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…
Phase: NA • Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Dye test helps spine surgeons see if They've cleaned enough
Knowledge-focused CompletedThis study tested whether injecting a contrast dye into the disc space during TLIF spine surgery helps surgeons assess how well they have removed the disc. 56 patients having spinal fusion for degenerative spine disease were randomly assigned to either have the dye used as a chec…
Phase: NA • Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedThis completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Study reveals which activities help or harm back pain
Knowledge-focused CompletedThis completed study looked at 416 veterans with low back pain to find out which physical activities cause short-term pain flares and which help long-term recovery. Participants reported their pain flares and disability over time. The goal is to give better activity advice to peo…
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Blood flow measure may predict neck pain block success
Knowledge-focused CompletedThis completed study with 92 people tested whether a measure called perfusion index (a way to check blood flow) can predict how well a nerve block (erector spinae plane block) relieves chronic neck pain from conditions like herniated discs or spinal narrowing. Researchers tracked…
Sponsor: Keimyung University Dongsan Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Mind, spirit, and pain: new study explores what chronic pain patients really believe
Knowledge-focused CompletedThis study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC