New spine implants tested for safety in patients with back problems
NCT ID NCT04420143
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at the safety and performance of two types of expandable spine implants (MLX and XLX ACR) in 109 adults with degenerative disc disease, spondylolisthesis, or scoliosis. Researchers tracked complications, bone fusion, and improvement in nerve symptoms after surgery. The goal was to understand how well these implants work over the medium to long term.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
expandable lumbar interbody implants (MLX and XLX ACR)
What this could lead to
If successful, this could confirm that these implants are safe and effective for treating degenerative spine conditions, offering a surgical option to reduce pain and improve function.
What could go wrong
This is a completed study with only 109 participants and no comparison group, so results may not apply to all patients. Risks include complications from surgery and implant failure.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Carolina NeuroSurgery & Spine Associates
Charlotte, North Carolina, 28204, United States
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Lyerly Neurosurgery
Jacksonville, Florida, 32207, United States
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OrthoCarolina Research Institute
Charlotte, North Carolina, 28207, United States
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Orthopaedic Specialty Institute
Orange, California, 92868, United States