Spine surgery showdown: which approach helps patients recover faster?

NCT ID NCT01024699

Completed Symptom relief Sponsor: NuVasive Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of spine surgery (XLIF and TLIF) in 55 adults with a slipped vertebra causing pain and leg symptoms. The goal was to see which procedure led to better function and less pain over two years. Results could help doctors choose the best surgical approach for each patient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgical procedure (XLIF or TLIF)
What this could lead to: If one procedure proves better, it could help surgeons choose the less painful or more effective option for patients with slipped vertebrae.
What could go wrong: This is a small, completed study with only 55 participants, so results may not apply to everyone. Surgery always carries risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

spondylolisthesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPONDYLOLISTHESIS

Contacts and locations

Locations

Celebration Florida Hospital

Kissimmee, Florida, 34747, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Northwest Orthopaedic Specialists, P.S.

Paducah, Kentucky, 42003, United States
Northwest Orthopaedic Specialists, P.S.

Spokane, Washington, 99208, United States
Orthopaedic Clinic-Riverside Campus, University of Minnesota

Minneapolis, Minnesota, 55454, United States
Spine and Sports Institute

Richland, Washington, 99352, United States
St. Joseph's/Candler Health System

Savannah, Georgia, 31405, United States
St. Vincent-Jacksonville

Jacksonville, Florida, 32204, United States
The Methodist Hospital

Houston, Texas, 77030, United States

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