Spine surgery showdown: which approach helps patients recover faster?

NCT ID NCT01024699

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of spine surgery (XLIF and TLIF) in 55 adults with a slipped vertebra causing pain and leg symptoms. The goal was to see which procedure led to better function and less pain over two years. Results could help doctors choose the best surgical approach for each patient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgical procedure (XLIF or TLIF)

What this could lead to

If one procedure proves better, it could help surgeons choose the less painful or more effective option for patients with slipped vertebrae.

What could go wrong

This is a small, completed study with only 55 participants, so results may not apply to everyone. Surgery always carries risks like infection or nerve damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SPONDYLOLISTHESIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

spondylolisthesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Celebration Florida Hospital

    Kissimmee, Florida, 34747, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Northwest Orthopaedic Specialists, P.S.

    Paducah, Kentucky, 42003, United States

  • Northwest Orthopaedic Specialists, P.S.

    Spokane, Washington, 99208, United States

  • Orthopaedic Clinic-Riverside Campus, University of Minnesota

    Minneapolis, Minnesota, 55454, United States

  • Spine and Sports Institute

    Richland, Washington, 99352, United States

  • St. Joseph's/Candler Health System

    Savannah, Georgia, 31405, United States

  • St. Vincent-Jacksonville

    Jacksonville, Florida, 32204, United States

  • The Methodist Hospital

    Houston, Texas, 77030, United States