Experimental bone putty for spinal surgery falls short in early trial

NCT ID NCT01335243

Terminated Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a special bone graft material (MatriBONE mixed with the patient's own bone marrow) for spinal fusion surgery in people with painful degenerative back problems. The goal was to see how well the bones fused together after 12 months. However, the trial was stopped early, so we don't have clear results on whether it worked better than standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MatriBONE (a collagen scaffold with tri-calcium phosphate) combined with the patient's own bone marrow
What this could lead to: If successful, this approach could offer a safer alternative to traditional bone grafts for spinal fusion surgery.
What could go wrong: The trial was terminated early, so we don't have enough data to know if it works. It was also a small, early-phase study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ankylosis arthropathy lumbar disk degenerative disorder lumbar disk disease lumbar spinal stenosis osteoarthritis Pain spondylolisthesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE LUMBAR VERTEBRA DEGENERATIVE OSTEOARTHRITIS

Contacts and locations

Locations

Unité d'Orthopédie-Traumatologie rachis II, Pellegrin

Bordeaux, 33076, France

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