Severe cutaneous adverse reaction
MONDO:0005594A group of skin disorders including Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (GBFDE).
Also known as: SCAR
65 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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New surgical trick may improve nose shape after cleft lip repair
Disease control CompletedThis study tested a surgical technique called a dermal roll flap to support the nostril base in 45 people who had a previous cleft lip repair. The flap uses extra skin from the lip to lift and stabilize the nostril on the cleft side. Researchers measured changes in nostril positi…
Phase: NA • Sponsor: King Edward Medical University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Can a lung drug stop COVID scarring?
Disease control CompletedThis study tested whether nintedanib, a drug used for other lung diseases, can slow down lung damage in people who had severe COVID-19. It included 103 adults who still had lung problems more than 30 days after their COVID diagnosis. The main goal was to see if the drug helped ma…
Phase: PHASE4 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Can botox keep scars away? new study tests different doses
Prevention CompletedThis study tested whether injecting botulinum toxin type A (like Botox) into surgical wounds can prevent scars from forming. Fifty patients with emergency trauma or skin lumps received different doses (1, 2.5, or 5 units) or a placebo. Researchers measured scar appearance using a…
Phase: EARLY_PHASE1 • Sponsor: Qilu Hospital of Shandong University • Aim: Prevention
Last updated Jun 26, 2026 16:09 UTC
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DIY bandage change: could self-dressing heal foot ulcers just as well?
Symptom relief CompletedThis study tested whether people with diabetic foot ulcers can safely change their own dressings compared to having a nurse do it. Sixty adults with mild to moderate ulcers were randomly assigned to either self-dressing or nurse-led dressing. The researchers tracked healing time,…
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Laser vs. IPL: which zaps red scars best?
Symptom relief CompletedThis study tested two light-based treatments—long-pulsed ND:YAG laser and intense pulsed light (IPL)—on red scars from injuries or surgery. Forty people with scars on the head or neck received four sessions, one month apart. The goal was to see which treatment reduces redness mor…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Laser zaps scars, gets vets back on their feet
Symptom relief CompletedThis small study tested whether a special laser treatment can help veterans with leg amputations who have painful scars that make wearing their artificial limb hard. Ten veterans received the laser therapy, and researchers measured changes in pain, scar appearance, walking abilit…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Massage your scar, heal your pelvis: new study tests simple postpartum fix
Symptom relief CompletedThis study looked at whether a larger trial on self-scar massage for women after childbirth is possible. 14 new mothers with healed episiotomy or perineal tears were asked to massage their scar tissue at home for 6 weeks. The goal was to see if women would stick with the routine …
Phase: NA • Sponsor: University of Calgary • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Insulin dressing shows promise for diabetic foot ulcers
Symptom relief CompletedThis study tested whether applying insulin directly to diabetic foot ulcers helps them heal better than standard saline dressings. Thirty adults with diabetes and foot ulcers participated. Researchers measured healing rates and whether surgery was needed.
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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C-Section scar showdown: researchers test three stitches for best healing
Symptom relief CompletedThis study looked at 300 women who had a C-section to find out which type of stitch (Vicryl, Monocryl, or Prolene) works best for closing the skin. The goal was to see which stitch leads to fewer wound infections and better-looking scars. Researchers checked for infection 10 days…
Phase: NA • Sponsor: Ayşenur Çalış Özbayram • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New skin device shows promise for wrinkle and pigment reduction
Symptom relief CompletedThis completed trial tested the BTL-785F device on 39 healthy adults over 30 who wanted better skin on their face and neck. Participants received three treatments, each lasting 20–60 minutes, spaced 2–6 weeks apart. The goal was to see if the device could improve skin texture, re…
Phase: NA • Sponsor: BTL Industries Ltd. • Aim: Symptom relief
Last updated Jun 26, 2026 17:30 UTC
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Can collagen shots smooth scars and wrinkles? new study says maybe.
Symptom relief CompletedThis study tested whether injections of a collagen powder (HTIC) from cows could improve the look of scars, skin thinning, and volume loss on the face, neck, chest, and hands. Forty-five adults received a series of small injections under the skin. Researchers measured changes in …
Phase: NA • Sponsor: Centro Studi Dermatologici S.r.l. • Aim: Symptom relief
Last updated Jun 26, 2026 13:54 UTC
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Do future doctors know the skin risks of tattoos and piercings?
Knowledge-focused CompletedThis study surveys medical students to understand their attitudes toward tattoos and piercings and measure their awareness of related skin risks, such as infections, allergic reactions, and scarring. Researchers aim to see if students have adequate knowledge and how their views d…
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Should you remove your face bandage after 6 hours? new study investigates
Knowledge-focused CompletedThis study tested whether removing a wound dressing just 6 hours after facial skin surgery is better than keeping it covered for 7 days. 144 adults with benign skin lesions like moles or cysts were randomly assigned to one of the two methods. Researchers checked for swelling, red…
Phase: NA • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Micro-biopsies may revolutionize skin grafting
Knowledge-focused CompletedThis pilot study tested how skin heals after taking very small biopsies, called micro-biopsies, which are smaller than a sewing pin. Eight healthy adults scheduled for tummy tuck surgery had these micro-biopsies taken from skin that would later be removed. The goal was to see if …
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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AI boosts doctor accuracy for rare skin diseases in new study
Knowledge-focused CompletedThis study tested whether an artificial intelligence (AI) tool could help doctors diagnose rare and tricky skin conditions like generalized pustular psoriasis (GPP). Fifteen doctors, including both general practitioners and dermatologists, looked at 100 skin images. They first ga…
Sponsor: AI Labs Group S.L • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Your skin type may predict how well you heal after surgery
Knowledge-focused CompletedThis study looked at 173 Chinese patients to see if their skin type (based on the Baumann Skin Type system) affects how well they heal and scar after facial surgery for benign growths like moles or cysts. Researchers checked wound healing at 7 days and scar quality at 90 days usi…
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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AI could cut skin specialist wait times, study hints
Knowledge-focused CompletedThis study tested an artificial intelligence algorithm designed to help primary care doctors decide whether a patient with a skin condition really needs to see a dermatologist. Researchers enrolled 200 adults with skin problems and had their doctors take photos of the affected ar…
Sponsor: AI Labs Group S.L • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Skin serum showdown: which one boosts cell turnover?
Knowledge-focused CompletedThis study tested 5 different serums on 30 healthy Chinese women to see how well they help renew skin cells. Participants applied the serums daily for 21 days, and a dermatologist checked the treated areas under UV light. The goal was simply to measure skin cell renewal, not to t…
Phase: NA • Sponsor: BEIJING YUANBEN INFORMATION CONSULTING CO., LTD • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:51 UTC