Can collagen shots smooth scars and wrinkles? new study says maybe.

NCT ID NCT07153393

Completed Symptom relief Sponsor: Centro Studi Dermatologici S.r.l. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether injections of a collagen powder (HTIC) from cows could improve the look of scars, skin thinning, and volume loss on the face, neck, chest, and hands. Forty-five adults received a series of small injections under the skin. Researchers measured changes in appearance using a standard scale and also checked for pain and satisfaction. The goal was to see if this simple procedure could offer a safe way to rejuvenate skin without surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Type I bovine collagen (HTIC) injections
What this could lead to: If successful, this could offer a non-surgical option to improve the appearance of scars and age-related skin changes on the face and hands.
What could go wrong: This is a small, single-arm study with no comparison group, so results may not be generalizable. The treatment is cosmetic and not a cure for underlying skin conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATROPHIC SCAR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

severe cutaneous adverse reaction skin atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATROPHIC SCAR CICATRIX SCARS SKIN AGING OF FACE AND HANDS

Contacts and locations

Locations

Azienda Ospedaliera Federico II

Naples, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.