Rumination disorder

This study is testing whether two questionnaires (SCOFF-F and EDE-Q) can accurately detect eating disorders in pregnant women, separating them from normal pregnancy-related eating concerns. Researchers will compare answers from 50 pregnant women with and without diagnosed eating …

This study tests whether adding a mobile app and digital monitoring to standard group therapy can better prevent suicide risk in women with eating disorders. Researchers will compare two groups of 150 women aged 18-65 who have recently had suicidal thoughts or attempts. One group…

This trial explores whether a non-invasive device that delivers mild electrical stimulation to the head can help reduce anxiety before meals in adults hospitalized for eating disorders. Participants will use the Alpha-Stim AID device for 20-minute sessions before breakfast, lunch…

This study tests whether adding dramatherapy—using role play, improvisation, and creative exercises—to a standard exercise program improves quality of life for adults with obesity and eating disorders. Participants are in medical or bariatric care and will be randomly assigned to…

This study tests whether a text message program that helps people reduce 'safety behaviors' (like checking mirrors or seeking reassurance) can lessen appearance anxiety, body dysmorphic symptoms, and related eating or social anxiety issues. About 300 adults with high appearance c…

This study tests a mobile app designed to help adults with eating disorders stay motivated and ready for treatment while they are on a waitlist. Participants will either use the app for four weeks or continue with standard waitlist care. The goal is to see if the app can prevent …

This study tests whether AI-generated audio stories can help people with anxiety and fear of failure. Forty adults will listen to personalized scenarios based on childhood memories of criticism, with one version including a therapeutic twist where a supportive figure steps in. Th…

This study tests whether combining mindfulness meditation with real-time brain scan feedback can help teens with depression. Researchers will train 90 adolescents aged 13-18 to control brain circuits linked to rumination (repetitive negative thinking). The goal is to see if this …

This study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…

This study tests a 6-week virtual program called the Diabetes Body Project 2, designed to prevent eating disorders in women aged 18-40 with type 2 diabetes. The program includes weekly group sessions and home exercises to improve body image and reduce disordered eating. Researche…

This study tests whether a zinc-containing syrup (Biolizin) can improve eating habits in children aged 6 to 36 months who have poor appetite without a known medical cause. About 110 children will take the supplement or receive standard care for 42 days. Researchers will measure c…

This study compares two types of talk therapy for teenagers with eating disorders: enhanced cognitive-behavior therapy and family-based treatment. About 200 adolescents will be randomly assigned to one of the two therapies. The goal is to see if cognitive-behavior therapy works a…

This study tests a culturally and language-adapted internet-based cognitive behavioral therapy (i-CBT) for Farsi/Dari-speaking youth migrants and refugees aged 15-29. The goal is to reduce symptoms of common mental health problems like anxiety, depression, and stress. Participant…

This study tests a new way to treat eating disorders by personalizing therapy based on each person's most troubling symptoms. Researchers use smartphone surveys to map individual symptom patterns, then match participants to specific therapy modules. The goal is to see if this tai…

This study tests whether adding a peer coach or parent coach to standard eating disorder therapy helps teens aged 12-18 recover faster. 70 participants will receive 12 weeks of therapy plus either a parent coach with patient education materials or patient coaching with parent edu…

This pilot study tests whether artificial intelligence can create personalized therapy scripts to help adults reframe painful memories of childhood criticism. Eighty participants with anxiety will listen to AI-generated audio scenarios based on their own memories. Half will recei…

This study at the University of Pennsylvania is testing whether personalized brain stimulation can reduce negative emotions in people with depression and anxiety. Researchers will use brain scans to map each participant's negative emotion patterns, then apply different types of t…

This study looks at how a mindfulness app might help teenagers (ages 13-18) who tend to ruminate—getting stuck in repetitive negative thoughts. Participants will be randomly assigned to use the app or a control activity, and will have brain scans and cognitive tests before and af…

This study looks at how certain thinking patterns, called metacognitive beliefs, relate to eating disorders in teenagers. Researchers will compare 72 girls aged 12-17 who have an eating disorder with a similar group of girls without one. The goal is to understand if these thought…

This study tests whether combining a one-time session of brain stimulation (rTMS or electrical scalp stimulation) with emotion regulation training helps people with mood, anxiety, or related disorders better control their emotions. 240 participants will learn either cognitive res…

This study looks at how different front-of-pack nutrition labels—warning labels versus traffic light labels—affect food choices and negative emotions in people with eating disorders. Around 246 UK adults with a current or past eating disorder will make hypothetical food choices o…

This pilot study aims to see how common Barrett's esophagus is in people with eating disorders who have been purging (vomiting or ruminating) for at least 5 years. Researchers will use a simple, non-endoscopic device called EsoGuard to collect cell samples from the esophagus. The…

This study explores whether a sham (fake) neurofeedback system in virtual reality can change brain activity related to attention. About 35 adults with rumination or chronic pain will undergo EEG recordings while experiencing positive, negative, or no feedback. The goal is to see …

This study interviews 30 competitive athletes to learn what they believe causes and triggers eating disorders in sports. Half of the participants have had an eating disorder, and half have not. The goal is to compare their experiences and gather ideas on how to better prevent the…