Rumination disorder
MONDO:0001301Rumination disorder is the backward flow of recently eaten food from the stomach to the mouth. The food is then re-chewed and swallowed or spat out. A non-purposeful contraction of stomach muscles is involved in rumination. It may be initially triggered by a viral illness, emotional distress, or physical injury. In many cases, no underlying trigger is identified. Behavioral therapy is the mainstay of treatment.
Also known as: rumination, rumination syndrome
94 clinical trials for this condition and its sub-types.
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Could home therapy replace hospital stays for kids with mental health issues?
Disease control OngoingThis study tests whether intensive home-based psychiatric treatment can help children and teens with mental health disorders as an alternative to being in the hospital. Over 3 months, participants receive 3 to 7 home visits per week from a team of doctors, therapists, and other s…
Phase: NA • Sponsor: Medical University Innsbruck • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Can rewriting your life story improve mental health? small trial tests new therapy
Symptom relief OngoingThis study tests a therapy called RETELL that helps people with severe mental illness explore and reshape their life stories. The goal is to improve personal recovery, quality of life, and identity. Twenty adults with conditions like schizophrenia, bipolar disorder, or PTSD will …
Phase: NA • Sponsor: University of Aarhus • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Can talking about your thoughts help treat eating disorders?
Symptom relief OngoingThis pilot study is testing a type of talk therapy called Metacognitive Interpersonal Therapy (MIT-ED) for adults with various eating disorders, including those who are underweight. The therapy aims to help people understand and manage the negative thoughts and feelings that driv…
Phase: NA • Sponsor: GLORIA FIORAVANTI • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Pen and paper power: journaling may supercharge psychotherapy
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether adding a structured therapy journal to standard cognitive behavioral therapy (CBT) helps people with mental health conditions like depression, anxiety, or eating disorders feel better faster. About 80 adults in outpatient therapy will be randomly assig…
Phase: NA • Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Can acting out help heal? drama therapy trial targets dual diagnosis
Symptom relief TerminatedThis pilot study tests a specific type of drama therapy for people who have both a mental health condition (like depression or bipolar disorder) and a substance use disorder. Ten participants will attend weekly group drama therapy sessions for 12 weeks, then put on a performance.…
Phase: NA • Sponsor: Boston Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Peer mentors tested to ease tough eating disorder care transition
Symptom relief OngoingThis study looks at whether peer mentors can support youth aged 16-24 with eating disorders as they move from youth to adult treatment. Participants are paired with a mentor for 3-6 months. The goal is to see if this approach is practical and helps keep patients motivated.
Phase: NA • Sponsor: Nova Scotia Health Authority • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Can a 'Courage and Love' group therapy beat loneliness in seniors?
Symptom relief OngoingThis study tests a group therapy called Awareness, Courage, and Love (ACL) for older adults with psychiatric disorders who feel lonely. The therapy focuses on mindfulness, sharing feelings, and building connections. Researchers want to see if the program is practical and helpful …
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New Self-Guided program aims to help eating disorder patients tune into body signals
Symptom relief OngoingThis pilot study tests a new self-guided program called RISE, designed to help people with eating disorders better sense and understand their body's internal signals, like hunger and fullness. The program includes four online modules with relaxation exercises, emotion management,…
Phase: NA • Sponsor: Auburn University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Can peers help people recover from mental illness? new study says maybe
Knowledge-focused OngoingThis study tests a 10-week program called 'Grow to Recovery' for people with mental illness. The program is co-led by a peer (someone who also has a mental illness) and a professional. Researchers want to see if it helps participants feel more hopeful and capable. 138 people are …
Phase: NA • Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Brain scans and a new drug combo aim to break the cycle of depressive rumination
Knowledge-focused OngoingThis study looks at whether adding aripiprazole to the antidepressant escitalopram can reduce pathological rumination—repetitive, intrusive negative thoughts—in people with major depressive disorder. 108 participants will receive either escitalopram alone or escitalopram plus ari…
Phase: NA • Sponsor: Central South University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Mind over knee pain? study probes link between worry and osteoarthritis suffering
Knowledge-focused OngoingThis observational study looks at 103 adults with knee osteoarthritis to see if repetitive negative thinking (rumination and worry) is linked to worse pain and disability, even when X-ray damage is similar. Participants fill out questionnaires about their thoughts, pain, and dail…
Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Estrogen patches tested for brain effects in eating disorders
Knowledge-focused OngoingThis study looks at whether estrogen patches can improve mental flexibility and reward processing in young women (ages 14-35) with eating disorders linked to low estrogen. About 120 participants will receive either estrogen patches or placebo for 12 weeks. The goal is to understa…
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Parents' phone videos may unlock better feeding disorder care
Knowledge-focused ENROLLING_BY_INVITATIONThis study gathers home videos, images, and daily logs from parents of 1,000 children with feeding difficulties. The goal is to help doctors monitor progress remotely and build a database for future research. Participants must already be using the CHAMP App in another study.
Sponsor: Children's Mercy Hospital Kansas City • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Can a simple phone call prevent eating disorder relapse?
Knowledge-focused OngoingThis study follows 250 patients who have recovered from an eating disorder. Nurses will call them once a year for three years to check on their health and see if they relapse. The goal is to learn what factors might increase the risk of relapse, such as age or exercise habits.
Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Ottawa study aims to help homeless youth cut back on tobacco and drugs
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at tobacco, cannabis, and other drug use among homeless and at-risk youth in downtown Ottawa. Researchers will follow 520 participants aged 16 and older who are homeless or insecurely housed and have a history of cannabis use and mental illness. The goal is to un…
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Which therapy works best for troubled teens? new study aims to find out
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 192 teens aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over 9 months. The goal is to…
Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC